关于 "Cytoskeleton & Motor Proteins" 的结果285+ 个结果
- Acetyl-Amyloid β-Protein (1-6) amideCAS: 903883-22-7
Experiments using sub-peptides of Aβ42 revealed that the epitope identified by the antibody A8, as described by Ying and coworkers, lies within the 1-6 region of Aβ. The antibody displays high affinity for soluble Aβ42 oligomers in the molecular weight range of 16.5-25 kDa, and detected target antigen in brain sections from senescence-accelerated SAMP 8 mice. Amidated or acetylated and amidated forms of the sequence were used for example for quantitative structure retention relationships (QSRR) experiments. The latter could allow prediction of reversed-phase high-performance liquid chromatography (HPLC) retention of peptides, as reported by Kaliszan and coworkers.
- Melanocyte Protein PMEL 17 (130-138) (human)CAS: 162558-08-9
PMEL 17 could be a melanogenic enzyme. This sequence has been identified as a gp100 epitope that is recognized in the context of HLA-A2 by tumor-infiltrating lymphocytes (TIL) in vivo.
- Amyloid β/A4 Protein Precursor₇₇₀ (667-676)CAS: 252256-37-4
The peptide substrate APP (667-676), SEVKMDAEFR, corresponds to the wild-type amyloid precursor protein (APP) β-secretase cleavage site. SEVKMDAEFR has been used for assaying β-secretase activity.
- Amyloid β/A4 Protein Precursor₇₇₀ (740-770)CAS: 1802086-24-3
Amyloid β/A4 Protein Precursor??? (740-770) corresponds to a C-terminal amyloid precursor protein (APP) fragment known as C31. This fragment is intracellularly generated by proteolytic cleavage of APP by caspases-8 and -9. C31 had a proapoptotic and a cytotoxic effect on neuronal cells and was shown to be present in brains of Alzheimer's disease (AD) patients. In cultured cells caspase cleavage of APP was induced by amyloid β-protein and the subsequent generation of C31 contributed to the apoptotic cell death associated with amyloid β-protein. Amyloid precursor binding protein BP1 (APP-BP1) a cell cycle protein which is increased in AD brain was demonstrated to bind to the C31 region of APP and to mediate APP-induced apoptosis.
- Biotinyl-εAhx-Amyloid β-Protein (1-40)CAS: 1802086-72-1
The flexible LC spacer increases the accessibility of the biotin moiety.
- Biotinyl-εAhx-Amyloid β-Protein (1-42)
The flexible LC spacer increases the accessibility of the biotin moiety.
- HCV NS4A Protein (21-34) (JT strain)CAS: 176260-88-1
The NS4A fragment GSVVIVGRIILSGR corresponds to the residues involved in the interaction with the NS3 protease. Unlike the NS4A fragment (22-34) derived from the H strain (H-2764), this peptide contains no cysteine residues and is hence more stable.
- HCV NS4A Protein (22-34) (H strain)CAS: 290832-54-1
The fragment 22-34 encompassing the central region of HCV NS4A protein possesses proteinase cofactor activity in vitro. HCV NS4A Protein (22-34) was found to be able to substitute for intact NS4A protein in a cell-free trans cleavage assay.
- 3-Phosphoglyceric Phosphokinase(BR，1000u/mg protein)CAS: 9001-83-6
活力定义：One unit will convert 1.0 μmole of 1,3-diphosphoglycerate to 3-phosphoglycerate per min at pH 6.9 at 25 °C.
- L-amino acid oxidase(≥4u/mg protein)CAS: 9000-89-9
活力定义：One Unit oxidizes one micormole of L-leucine per minute at 25°C, pH 7.6。
- N-Acetylneuraminic acid aldolase(≥ 45U/mg protein)CAS: 9027-60-5
介绍： One unit will convert one micromole of NAcetylneuraminate to N-Acetyl-Dmannosamine per minute at pH 7
- β-N-Acetylglucosaminidase(BR,15u/mg protein)CAS: 9012-33-3
酶活定义：One unit will hydrolyze 1.0 μmole of p-nitrophenyl N-acetyl-β-D-glucosaminide to p-nitrophenol and N-acetyl-D-glucosamine per min at pH 5.0 at 25 °C.
- Activated Protein C (390-404), human TFA
Activated Protein C (390-404), human TFA 是一种维生素 K 依赖的丝氨酸蛋白酶活化蛋白 C (APC) 的多肽片段，可抑制 APC 的抗凝血活性。
- Calmodulin-Dependent Protein Kinase II 281-309CAS: 116826-37-0
Calmodulin-Dependent Protein Kinase II (281-309) 是钙/钙调素依赖蛋白激酶 II (CaM kinase II) 多肽片段。
- CEF1, Influenza Matrix Protein M1 58-66CAS: 141368-69-6
CEF1, Influenza Matrix Protein M1 (58-66) 是源于甲型流感病毒 (influenza A virus) 的基质蛋白表位。
- Human Papillomavirus (HPV) E7 protein 49-57CAS: 151812-18-9
Human Papillomavirus (HPV) E7 protein (49-57) 是 H-2d 限制性人乳头瘤病毒 (HPV) E749-57 表位（即在 E7 蛋白中跨越 49 到 57 个氨基酸残基的短肽）。
- Interphotoreceptor retinoid-binding protein(668-687) TFA
Interphotoreceptor retinoid-binding protein(668-687) TFA 是光受体视黄醇类结合蛋白的 668 到 687 氨基酸序列，可诱发葡萄膜炎。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GA20535 | Acetyl-Amyloid β-Protein (1-6) amide | 903883-22-7 | Amyloid β protein | ||
Experiments using sub-peptides of Aβ42 revealed that the epitope identified by the antibody A8, as described by Ying and coworkers, lies within the 1-6 region of Aβ. The antibody displays high affinity for soluble Aβ42 oligomers in the molecular weight range of 16.5-25 kDa, and detected target antigen in brain sections from senescence-accelerated SAMP 8 mice. Amidated or acetylated and amidated forms of the sequence were used for example for quantitative structure retention relationships (QSRR) experiments. The latter could allow prediction of reversed-phase high-performance liquid chromatography (HPLC) retention of peptides, as reported by Kaliszan and coworkers. | |||||
| GA23185 | Melanocyte Protein PMEL 17 (130-138) (human) | 162558-08-9 | - | ||
PMEL 17 could be a melanogenic enzyme. This sequence has been identified as a gp100 epitope that is recognized in the context of HLA-A2 by tumor-infiltrating lymphocytes (TIL) in vivo. | |||||
| GA23206 | Myelin Basic Protein (85-99) Peptide Antagonist | 444305-16-2 | - | ||
An MBP (85-99) antagonist | |||||
| GA23471 | rec pTH-Related Protein (1-86) (human) | - | - | ||
pTHrP (1-86) increased bone formation in vitro. | |||||
| GA21462 | FITC-εAhx-Amyloid β-Protein (1-42) | - | Amyloid β protein | ||
| GA20718 | Amyloid β/A4 Protein Precursor₇₇₀ (667-676) | 252256-37-4 | Amyloid β protein | ||
The peptide substrate APP (667-676), SEVKMDAEFR, corresponds to the wild-type amyloid precursor protein (APP) β-secretase cleavage site. SEVKMDAEFR has been used for assaying β-secretase activity. | |||||
| GA20719 | Amyloid β/A4 Protein Precursor₇₇₀ (740-770) | 1802086-24-3 | Amyloid β protein | ||
Amyloid β/A4 Protein Precursor??? (740-770) corresponds to a C-terminal amyloid precursor protein (APP) fragment known as C31. This fragment is intracellularly generated by proteolytic cleavage of APP by caspases-8 and -9. C31 had a proapoptotic and a cytotoxic effect on neuronal cells and was shown to be present in brains of Alzheimer's disease (AD) patients. In cultured cells caspase cleavage of APP was induced by amyloid β-protein and the subsequent generation of C31 contributed to the apoptotic cell death associated with amyloid β-protein. Amyloid precursor binding protein BP1 (APP-BP1) a cell cycle protein which is increased in AD brain was demonstrated to bind to the C31 region of APP and to mediate APP-induced apoptosis. | |||||
| GA20854 | Biotinyl-εAhx-Amyloid β-Protein (1-40) | 1802086-72-1 | Amyloid β protein | ||
The flexible LC spacer increases the accessibility of the biotin moiety. | |||||
| GA20855 | Biotinyl-εAhx-Amyloid β-Protein (1-42) | - | Amyloid β protein | ||
The flexible LC spacer increases the accessibility of the biotin moiety. | |||||
| GA22151 | HCV NS4A Protein (21-34) (JT strain) | 176260-88-1 | - | ||
The NS4A fragment GSVVIVGRIILSGR corresponds to the residues involved in the interaction with the NS3 protease. Unlike the NS4A fragment (22-34) derived from the H strain (H-2764), this peptide contains no cysteine residues and is hence more stable. | |||||
| GA22152 | HCV NS4A Protein (22-34) (H strain) | 290832-54-1 | - | ||
The fragment 22-34 encompassing the central region of HCV NS4A protein possesses proteinase cofactor activity in vitro. HCV NS4A Protein (22-34) was found to be able to substitute for intact NS4A protein in a cell-free trans cleavage assay. | |||||
| GA22604 | HIV-1 gag Protein p24 (194-210) | 141281-67-6 | - | ||
| GB10001 | 3-Phosphoglyceric Phosphokinase(BR，1000u/mg protein) | 9001-83-6 | - | ||
活力定义：One unit will convert 1.0 μmole of 1,3-diphosphoglycerate to 3-phosphoglycerate per min at pH 6.9 at 25 °C.
| |||||
| GB10069 | L-amino acid oxidase(≥4u/mg protein) | 9000-89-9 | - | ||
活力定义：One Unit oxidizes one micormole of L-leucine per minute at 25°C, pH 7.6。
| |||||
| GB10083 | N-Acetylneuraminic acid aldolase(≥ 45U/mg protein) | 9027-60-5 | - | ||
介绍： One unit will convert one micromole of NAcetylneuraminate to N-Acetyl-Dmannosamine per minute at pH 7 | |||||
| GB10147 | β-N-Acetylglucosaminidase(BR,15u/mg protein) | 9012-33-3 | - | ||
酶活定义：One unit will hydrolyze 1.0 μmole of p-nitrophenyl N-acetyl-β-D-glucosaminide to p-nitrophenol and N-acetyl-D-glucosamine per min at pH 5.0 at 25 °C.
| |||||
| GC35246 | Activated Protein C (390-404), human TFA | - | Peptides | ||
Activated Protein C (390-404), human TFA 是一种维生素 K 依赖的丝氨酸蛋白酶活化蛋白 C (APC) 的多肽片段，可抑制 APC 的抗凝血活性。 | |||||
| GC35595 | Calmodulin-Dependent Protein Kinase II 281-309 | 116826-37-0 | Peptides | ||
Calmodulin-Dependent Protein Kinase II (281-309) 是钙/钙调素依赖蛋白激酶 II (CaM kinase II) 多肽片段。 | |||||
| GC35639 | CEF1, Influenza Matrix Protein M1 58-66 | 141368-69-6 | Influenza virus | ||
CEF1, Influenza Matrix Protein M1 (58-66) 是源于甲型流感病毒 (influenza A virus) 的基质蛋白表位。 | |||||
| GC36264 | Human Papillomavirus (HPV) E7 protein 49-57 | 151812-18-9 | Peptides | ||
Human Papillomavirus (HPV) E7 protein (49-57) 是 H-2d 限制性人乳头瘤病毒 (HPV) E749-57 表位（即在 E7 蛋白中跨越 49 到 57 个氨基酸残基的短肽）。 | |||||
| GC36323 | Interphotoreceptor retinoid-binding protein(668-687) TFA | - | - | ||
Interphotoreceptor retinoid-binding protein(668-687) TFA 是光受体视黄醇类结合蛋白的 668 到 687 氨基酸序列，可诱发葡萄膜炎。 | |||||