关于 "Nucleoside Antimetabolite/Analogue" 的结果17+ 个结果
- GLPG0634 analogueCAS: 1206101-20-3
GLPG0634 类似物 (Compoun 176) 是一种广谱 JAK 抑制剂，对 JAK1、JAK2 和 JAK3 的 IC50 值 <100 nM。
- Phentolamine Analogue 1CAS: 47142-51-8
PhentolamineAnalogue1是phentolamine的类似物。Phentolamine是一种非选择性的alpha-adrenergic拮抗剂。
- Remdesivir nucleoside monophosphateCAS: 1911578-74-9
Remdesivir nucleoside monophosphate 是 Remdesivir 的代谢产物。Remdesivir 是一种具有抗 SARS-CoV 和 MERS-CoV 活性的核苷类似物。
- Nucleoside-5’-Triphosphate Set
1 (100 mM) vial each of ATP, CTP, GTP and UTPEach NTP is analyzed separately by AX-HPLC, RP-HPLC, 31P NMR and Mass Spec.
- CCT251545 analogue, Compound 51
Potent, Selective, orally bioavailable CDK 8/19 Inhibitor
- Kadsurin A analogue-1CAS: 155551-59-0
Kadsurin A analogue-1 (Compound 8) is a lignan can be extracted fromPiper argyrophylum.
- 2’-Deoxy-P-nucleoside-5’-Triphosphate
2’-Deoxy-P-nucleoside is a degenerate base which behaves as a universal pyrimidine and therefore base pairs with both adenine and guanine.
- GSK 461364 analogue IICAS: 929095-22-7
Potent Polo-like kinase (PLK) inhibitor, selective at PLK1 (IC50: 2 nM) over PLK3 (IC50: 270 nM)
- Purine-nucleoside phosphorylase(BR，100-200u/mg)CAS: 9030-21-1
它可以将核苷分解为碱基和戊糖-1-磷酸，该反应是可逆的。嘌呤核苷磷酸化酶在嘌呤核苷酸补救合成代谢中十分重要，在生物体中嘌呤核苷磷酸化酶的缺乏会导致T细胞功能的损伤。
- VPS34 inhibitor 1 (Compound 19)CAS: 1383716-46-8
VPS34 inhibitor 1 (Compound 19, PIK-III analogue) is a potent and selective inhibitor of VPS34 with an IC50 of 15 nM.
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC15846 | INCB024360 analogue | 914471-09-3 | IDO | ||
A selective IDO1 inhibitor | |||||
| GC17222 | GLPG0634 analogue | 1206101-20-3 | JAK | ||
GLPG0634 类似物 (Compoun 176) 是一种广谱 JAK 抑制剂，对 JAK1、JAK2 和 JAK3 的 IC50 值 <100 nM。 | |||||
| GC33956 | Nucleoside-Analog-1 | 876707-99-2 | HCV | ||
Nucleoside-Analog-1是抗病毒核苷R1479的类似物，用于HCV看病毒核苷类似物的合成。 | |||||
| GC33959 | Nucleoside-Analog-2 | 876708-01-9 | HCV | ||
Nucleoside-Analog-2是针对丙型肝炎病毒（HCV）复制的4'-叠氮胞苷类似物。 | |||||
| GC30740 | Phentolamine Analogue 1 | 47142-51-8 | Others | ||
PhentolamineAnalogue1是phentolamine的类似物。Phentolamine是一种非选择性的alpha-adrenergic拮抗剂。 | |||||
| GC67787 | Rezivertinib analogue 1 | 2227103-37-7 | Others | ||
Rezivertinib analogue 1 是一种甲磺酸奥希替尼的工艺杂质, 可用于非小细胞肺癌的研究。 | |||||
| GC36525 | Macitentan n-butyl analogue | 556797-16-1 | Endothelin Receptor | ||
Macitentan丁基类似物是Macitentan的丁基类似物。 | |||||
| GC39797 | Remdesivir nucleoside monophosphate | 1911578-74-9 | - | ||
Remdesivir nucleoside monophosphate 是 Remdesivir 的代谢产物。Remdesivir 是一种具有抗 SARS-CoV 和 MERS-CoV 活性的核苷类似物。 | |||||
| GC71809 | Nucleoside hydrolase (IAGNH) | 9025-44-9 | Endogenous Metabolite | ||
Nucleoside hydrolase (IAGNH)是一种糖苷酶。 | |||||
| GN20065 | Nucleoside-5’-Triphosphate Set | - | - | ||
1 (100 mM) vial each of ATP, CTP, GTP and UTPEach NTP is analyzed separately by AX-HPLC, RP-HPLC, 31P NMR and Mass Spec. | |||||
| GC18051 | CCT251545 analogue, Compound 51 | - | Cyclin-Dependent Kinases | ||
Potent, Selective, orally bioavailable CDK 8/19 Inhibitor | |||||
| GC77445 | Kadsurin A analogue-1 | 155551-59-0 | - | ||
Kadsurin A analogue-1 (Compound 8) is a lignan can be extracted fromPiper argyrophylum. | |||||
| GN20087 | 2’-Deoxy-P-nucleoside-5’-Triphosphate | - | - | ||
2’-Deoxy-P-nucleoside is a degenerate base which behaves as a universal pyrimidine and therefore base pairs with both adenine and guanine. | |||||
| GB40224 | GSK 461364 analogue II | 929095-22-7 | - | ||
Potent Polo-like kinase (PLK) inhibitor, selective at PLK1 (IC50: 2 nM) over PLK3 (IC50: 270 nM) | |||||
| GB10111 | Purine-nucleoside phosphorylase(BR，100-200u/mg) | 9030-21-1 | - | ||
它可以将核苷分解为碱基和戊糖-1-磷酸，该反应是可逆的。嘌呤核苷磷酸化酶在嘌呤核苷酸补救合成代谢中十分重要，在生物体中嘌呤核苷磷酸化酶的缺乏会导致T细胞功能的损伤。 | |||||
| GC12709 | XL147 | 956958-53-5 | Other Apoptosis | ||
An analog of XL147 | |||||
| GC26044 | VPS34 inhibitor 1 (Compound 19) | 1383716-46-8 | PI3K | ||
VPS34 inhibitor 1 (Compound 19, PIK-III analogue) is a potent and selective inhibitor of VPS34 with an IC50 of 15 nM. | |||||