关于 "Aurora Kinase" 的结果29+ 个结果
- Tyrosine kinase-IN-1CAS: 705946-27-6
Tyrosinekinase-IN-1是多靶点的酪氨酸激酶抑制剂，抑制KDR，Flt-1，FGFR1和PDGFRα的IC50值分别为4，20，4，2nM。
- Multi-target kinase inhibitor 2
Multi-target kinase inhibitor 2（化合物5K）是一种多靶点激酶抑制剂，对EGFR、Her2、VEGFR2和CDK2酶具有活性，IC50值在40至204 nM之间。
VEGFR - TIE-2/VEGFR-2 kinase-IN-1CAS: 453590-24-4
TIE-2/VEGFR-2 kinase-IN-1 用于合成 TIE-2 或者 VEGFR-2 抑制剂，从专利 WO2003022852 中获得，例 14。TIE-2/VEGFR-2 kinase-IN-1 用于研究不适当的血管生成相关疾病。
VEGFR - ChiauranibCAS: 1256349-48-0
Chiauranib (CS2164) selectively inhibits multiple kinase targets aurora B kinase (AURKB), colony-stimulating factor 1 receptor (CSF1R), and vascular endothelial growth factor receptor (VEGFR)/platelet-derived growth factor receptor (PDGFR)/c-Kit , thereby inhibiting the rapid proliferation of tumor cells, enhancing the antitumor immunity, and inhibiting tumor angiogenesis, to achieve the anti-tumor efficacy.
- PF-03814735CAS: 942487-16-3
PF-03814735 是一种有效的、具有口服生物利用度的 Aurora1 和 Aurora2 激酶的可逆抑制剂，IC50 值分别为 0.8nM 和 5nM 。
VEGFR - ENMD-2076 L-(+)-Tartaric acidCAS: 1291074-87-7
ENMD-2076 L-(+)-Tartaric acid 是一种多靶点激酶抑制剂，对 Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1 的 IC50 为 1.86、14、58.2、15.9、92.7、70.8、56.4 nM , FGFR2, Src, PDGFRα, 分别。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC34026 | Tyrosine kinase-IN-1 | 705946-27-6 | FGFR | ||
Tyrosinekinase-IN-1是多靶点的酪氨酸激酶抑制剂，抑制KDR，Flt-1，FGFR1和PDGFRα的IC50值分别为4，20，4，2nM。 | |||||
| GC74096 | MET kinase-IN-4 | 888719-03-7 | VEGFR | ||
MET kinase-IN-4是一种口服活性Met激酶抑制剂。 | |||||
| GC32469 | SU5408 (VEGFR2 Kinase Inhibitor I) | 15966-93-5 | VEGFR | ||
A potent, cell-permeable inhibitor of VEGFR2 | |||||
| GC16062 | VEGFR Tyrosine Kinase Inhibitor II | 269390-69-4 | VEGFR | ||
An inhibitor of KDR, FLT1, and c-Kit | |||||
| GC73264 | Multi-target kinase inhibitor 2 | - | VEGFR | ||
Multi-target kinase inhibitor 2（化合物5K）是一种多靶点激酶抑制剂，对EGFR、Her2、VEGFR2和CDK2酶具有活性，IC50值在40至204 nM之间。 | |||||
| GC60365 | TIE-2/VEGFR-2 kinase-IN-1 | 453590-24-4 | VEGFR | ||
TIE-2/VEGFR-2 kinase-IN-1 用于合成 TIE-2 或者 VEGFR-2 抑制剂，从专利 WO2003022852 中获得，例 14。TIE-2/VEGFR-2 kinase-IN-1 用于研究不适当的血管生成相关疾病。 | |||||
| GC10938 | AAL-993 | 269390-77-4 | VEGFR | ||
Inhibitor of VEGFR1, 2, and 3 | |||||
| GC16499 | Sorafenib Tosylate | 475207-59-1 | Other Apoptosis | ||
A multi-kinase inhibitor | |||||
| GC62145 | Chiauranib | 1256349-48-0 | c-FMS | ||
Chiauranib (CS2164) selectively inhibits multiple kinase targets aurora B kinase (AURKB), colony-stimulating factor 1 receptor (CSF1R), and vascular endothelial growth factor receptor (VEGFR)/platelet-derived growth factor receptor (PDGFR)/c-Kit , thereby inhibiting the rapid proliferation of tumor cells, enhancing the antitumor immunity, and inhibiting tumor angiogenesis, to achieve the anti-tumor efficacy. | |||||
| GC14683 | Sunitinib malate | 341031-54-7 | Autophagy | ||
A multi-kinase inhibitor | |||||
| GC16327 | Pazopanib (GW-786034) | 444731-52-6 | Autophagy | ||
A multi-kinase inhibitor | |||||
| GC18074 | PF-03814735 | 942487-16-3 | VEGFR | ||
PF-03814735 是一种有效的、具有口服生物利用度的 Aurora1 和 Aurora2 激酶的可逆抑制剂，IC50 值分别为 0.8nM 和 5nM 。 | |||||
| GC12145 | ENMD-2076 L-(+)-Tartaric acid | 1291074-87-7 | PDGFR | ||
ENMD-2076 L-(+)-Tartaric acid 是一种多靶点激酶抑制剂，对 Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1 的 IC50 为 1.86、14、58.2、15.9、92.7、70.8、56.4 nM , FGFR2, Src, PDGFRα, 分别。 | |||||
| GC32805 | Sulfatinib (HMPL-012) | 1308672-74-3 | VEGFR | ||
A multi-kinase inhibitor | |||||
| GC33087 | 2,4-Pyrimidinediamine with linker | 1430089-64-7 | VEGFR | ||
A multi-kinase inhibitor | |||||
| GC33173 | TAS-115 | 1190836-34-0 | c-MET | ||
A multi-kinase inhibitor | |||||
| GC33273 | TAS-115 mesylate (TAS-115 methanesulfonate) | 1688673-09-7 | c-MET | ||
A multi-kinase inhibitor | |||||
| GC18211 | Ningetinib | 1394820-69-9 | c-MET | ||
A multi-kinase inhibitor | |||||
| GC31752 | Tesevatinib (XL-647) | 781613-23-8 | Ephrin Receptor | ||
A multi-kinase inhibitor | |||||
| GC17959 | AZD2932 | 883986-34-3 | c-Kit | ||
A multi-kinase inhibitor | |||||
| GC10914 | AST 487 | 630124-46-8 | Bcr-Abl | ||
A multi-kinase inhibitor | |||||
| GC11763 | Telatinib (BAY 57-9352) | 332012-40-5 | PDGFR | ||
A multi-kinase inhibitor | |||||
| GC16000 | WHI-P180 | 211555-08-7 | EGFR | ||
A multi-kinase inhibitor | |||||
| GC34159 | Ilorasertib (ABT-348) | 1227939-82-3 | RET | ||
A multi-kinase inhibitor | |||||