关于 "CFTR" 的结果20 个结果
筛选:Ubiquitination/ Proteasome×
- CFTR corrector 2CAS: 1628416-28-3
FDL169 is a CFTR corrector that is designed to fix and restore the function of the defective CFTR protein.
- CFTRinh-172CAS: 307510-92-5
CFTRinh-172被鉴定为囊性纤维化跨膜传导调节因子(CFTR)Cl - 通道强效的选择性阻断剂。CFTRinh-172对野生型、G551D和G1349D CFTR的Cl - 电流具有抑制作用，K i 值为0.5μM。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC34532 | CFTR corrector 2 | 1628416-28-3 | Autophagy | ||
FDL169 is a CFTR corrector that is designed to fix and restore the function of the defective CFTR protein. | |||||
| GC35667 | CFTR corrector 1 | 2216712-66-0 | Autophagy | ||
An F508del-CFTR corrector and potentiator | |||||
| GC14421 | CFTRinh-172 | 307510-92-5 | Autophagy | ||
CFTRinh-172被鉴定为囊性纤维化跨膜传导调节因子(CFTR)Cl-通道强效的选择性阻断剂。CFTRinh-172对野生型、G551D和G1349D CFTR的Cl-电流具有抑制作用，Ki值为0.5μM。 | |||||
| GC17616 | PPQ-102 | 931706-15-9 | Autophagy | ||
A CFTR channel inhibitor | |||||
| GC12489 | Ivacaftor benzenesulfonate | 1134822-09-5 | Autophagy | ||
A CFTR potentiator | |||||
| GC13316 | Ivacaftor hydrate | 1134822-07-3 | Autophagy | ||
A CFTR potentiator | |||||
| GC10296 | Ivacaftor (VX-770) | 873054-44-5 | Autophagy | ||
A CFTR potentiator | |||||
| GC19169 | GLPG1837 | 1654725-02-6 | Autophagy | ||
A CFTR potentiator | |||||
| GC15455 | VX-809 | 936727-05-8 | Autophagy | ||
A F508del-CFTR corrector | |||||
| GC11229 | IOWH-032 | 1191252-49-9 | Autophagy | ||
A modulator of CFTR | |||||
| GC14914 | KM 11060 | 774549-97-2 | Autophagy | ||
A F508del-CFTR corrector | |||||
| GC17804 | GlyH-101 | 328541-79-3 | Autophagy | ||
A reversible CFTR channel blocker | |||||
| GC34745 | PTI-428 | 1953130-87-4 | Autophagy | ||
PTI-428是一种可增强并稳定囊性纤维化跨膜传导调节因子（CFTR）蛋白功能的特异性调节剂。 | |||||
| GC14920 | VX-661 | 1152311-62-0 | Autophagy | ||
An investigational compound that promotes the maturation of delta F508 CFTR | |||||
| GC36149 | GLPG2451 | 2055015-61-5 | Autophagy | ||
GLPG2451 是一种囊性纤维化跨膜电导调节器 (CFTR) 的增强剂，有效增强低温挽救的 F508del CFTR，EC50 为 11.1 nM。 | |||||
| GC30537 | BPO-27 racemate | 1314873-02-3 | Autophagy | ||
BPO-27racemate是有效的CFTR抑制剂，IC50值为8nM。 | |||||
| GC31665 | (R)-BPO-27 | 1415390-47-4 | Autophagy | ||
(R)-BPO-27是有效的CFTR抑制剂，IC50值为4nM。 | |||||
| GC73522 | Tezacaftor-d4 | 1961280-24-9 | Autophagy | ||
Tezacaftor-d4 (VX-661-d4)是氘标记的Tezacaftor， F508del CFTR校正器。 | |||||
| GC64358 | Olacaftor | 1897384-89-2 | Autophagy | ||
Olacaftor (VX-440) 是囊性纤维化跨膜电导调节因子 (CFTR) 的调节剂，来自专利US9782408。 | |||||
| GC12346 | PTC124(Ataluren) | 775304-57-9 | Autophagy | ||
Selective inducer of stop codon read-through | |||||