关于 "Endocrinology and Hormones" 的结果9+ 个结果
筛选:Tyrosine Kinase×
- XentuzumabCAS: 1417158-65-6
Xentuzumab (Anti-Human IGF1 and IGF2 Recombinant Antibody; BI836845) 是重组的人源化单克隆抗体，靶向 IGF 配体 IGF1 和 IGF2。Xentuzumab 抑制 IGF1 和 IGF2 的生长促进信号，抑制 AKT 的激活。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC70151 | Xentuzumab | 1417158-65-6 | IGF1R | ||
Xentuzumab (Anti-Human IGF1 and IGF2 Recombinant Antibody; BI836845) 是重组的人源化单克隆抗体，靶向 IGF 配体 IGF1 和 IGF2。Xentuzumab 抑制 IGF1 和 IGF2 的生长促进信号，抑制 AKT 的激活。 | |||||
| GC16580 | LDN-193189 | 1062368-24-4 | TGF-β Receptor | ||
An inhibitor of BMP receptors ALK1, ALK2, ALK3, and ALK6 | |||||
| GC36438 | Lenvatinib mesylate | 857890-39-2 | c-Kit | ||
An inhibitor of VEGFR2 and VEGFR3 | |||||
| GC11555 | ZM 323881 HCl | 193000-39-4 | VEGFR | ||
A potent and selective VEGFR2 inhibitor | |||||
| GC14464 | Vatalanib | 212141-54-3 | VEGFR | ||
A potent and selective VEGF receptor inhibitor | |||||
| GC13343 | Bosutinib (SKI-606) | 380843-75-4 | Autophagy | ||
An inhibitor of Src and Abl kinases | |||||
| GC10362 | Neratinib (HKI-272) | 698387-09-6 | EGFR | ||
A dual inhibitor of EGFR and HER2 | |||||
| GC11209 | Cerdulatinib (PRT062070) | 1198300-79-6 | Spleen Tyrosine Kinase (Syk) | ||
A dual inhibitor of Syk and JAKs | |||||
| GC48070 | SB-431542 (hydrate) | - | Cancer stem cell | ||
Inhibitor of receptors ALK4, ALK5, and ALK7 | |||||