关于 "Aurora Kinase" 的结果78+ 个结果
筛选:Tyrosine Kinase×
- ChiauranibCAS: 1256349-48-0
Chiauranib (CS2164) selectively inhibits multiple kinase targets aurora B kinase (AURKB), colony-stimulating factor 1 receptor (CSF1R), and vascular endothelial growth factor receptor (VEGFR)/platelet-derived growth factor receptor (PDGFR)/c-Kit , thereby inhibiting the rapid proliferation of tumor cells, enhancing the antitumor immunity, and inhibiting tumor angiogenesis, to achieve the anti-tumor efficacy.
- PF-03814735CAS: 942487-16-3
PF-03814735 是一种有效的、具有口服生物利用度的 Aurora1 和 Aurora2 激酶的可逆抑制剂，IC50 值分别为 0.8nM 和 5nM 。
- ENMD-2076 L-(+)-Tartaric acidCAS: 1291074-87-7
ENMD-2076 L-(+)-Tartaric acid 是一种多靶点激酶抑制剂，对 Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1 的 IC50 为 1.86、14、58.2、15.9、92.7、70.8、56.4 nM , FGFR2, Src, PDGFRα, 分别。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC11134 | ALW-II-41-27 | 1186206-79-0 | Ephrin Receptor | ||
ALW-II-41-27 是一种 Eph 家族酪氨酸激酶抑制剂，抑制 Eph2 的 IC50 为 11 nM。 | |||||
| GC44977 | Syk Inhibitor | 622387-85-3 | Src | ||
Potently blocks spleen tyrosine kinase activity | |||||
| GC44978 | Syk Inhibitor II | 726695-51-8 | 5-HT Receptor | ||
A selective blocker of spleen tyrosine kinase activity | |||||
| GC10938 | AAL-993 | 269390-77-4 | VEGFR | ||
Inhibitor of VEGFR1, 2, and 3 | |||||
| GC12058 | TCS 359 | 301305-73-7 | FLT3 | ||
A cell-permeable FLT3 inhibitor | |||||
| GC44583 | PD 089828 | 179343-17-0 | PDGFR | ||
An inhibitor of EGFR, PDGFβ, FGF, and c-Src | |||||
| GC19508 | BLU-782 | 2141955-96-4 | ALK | ||
BLU-782 是一种口服精准疗法，专门设计用于选择性靶向突变体 ALK2。 | |||||
| GC16957 | Src I1 | 179248-59-0 | Src | ||
A potent inhibitor of Src kinases | |||||
| GC11063 | BMX-IN-1 | 1431525-23-3 | BTK | ||
A selective BMX and BTK inhibitor | |||||
| GC16499 | Sorafenib Tosylate | 475207-59-1 | Other Apoptosis | ||
A multi-kinase inhibitor | |||||
| GC62145 | Chiauranib | 1256349-48-0 | c-FMS | ||
Chiauranib (CS2164) selectively inhibits multiple kinase targets aurora B kinase (AURKB), colony-stimulating factor 1 receptor (CSF1R), and vascular endothelial growth factor receptor (VEGFR)/platelet-derived growth factor receptor (PDGFR)/c-Kit , thereby inhibiting the rapid proliferation of tumor cells, enhancing the antitumor immunity, and inhibiting tumor angiogenesis, to achieve the anti-tumor efficacy. | |||||
| GC14683 | Sunitinib malate | 341031-54-7 | Autophagy | ||
A multi-kinase inhibitor | |||||
| GC16327 | Pazopanib (GW-786034) | 444731-52-6 | Autophagy | ||
A multi-kinase inhibitor | |||||
| GC10775 | MLR 1023 | 41964-07-2 | Src | ||
An allosteric Lyn kinase activator | |||||
| GC34708 | Pexidartinib hydrochloride | 2040295-03-0 | c-Kit | ||
A multi-targeted receptor tyrosine kinase inhibitor | |||||
| GC14592 | KW 2449 | 1000669-72-6 | Aurora Kinase | ||
A multi-kinase inhibitor | |||||
| GC18074 | PF-03814735 | 942487-16-3 | VEGFR | ||
PF-03814735 是一种有效的、具有口服生物利用度的 Aurora1 和 Aurora2 激酶的可逆抑制剂，IC50 值分别为 0.8nM 和 5nM 。 | |||||
| GC10638 | AT9283 | 896466-04-9 | Autophagy | ||
A broad spectrum kinase inhibitor | |||||
| GC12977 | Tyrphostin B44, (-) enantiomer | 133550-32-0 | EGFR | ||
EGFR-kinase inhibitor | |||||
| GC12145 | ENMD-2076 L-(+)-Tartaric acid | 1291074-87-7 | PDGFR | ||
ENMD-2076 L-(+)-Tartaric acid 是一种多靶点激酶抑制剂，对 Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1 的 IC50 为 1.86、14、58.2、15.9、92.7、70.8、56.4 nM , FGFR2, Src, PDGFRα, 分别。 | |||||
| GC32805 | Sulfatinib (HMPL-012) | 1308672-74-3 | VEGFR | ||
A multi-kinase inhibitor | |||||
| GC32808 | Selitrectinib (LOXO-195) | 2097002-61-2 | Trk | ||
A Trk kinase inhibitor | |||||
| GC33087 | 2,4-Pyrimidinediamine with linker | 1430089-64-7 | VEGFR | ||
A multi-kinase inhibitor | |||||
| GC33173 | TAS-115 | 1190836-34-0 | c-MET | ||
A multi-kinase inhibitor | |||||