关于 "Cancer stem cell" 的结果17+ 个结果

ALDH1A inhibitor; depletes CD133+ cancer stem cells (CSC)

A glomerular epithelial cell toxin

Z-VAD-FMK（苄氧羰基-Val-Ala-Asp（OMe）氟甲基酮），是一种类似ICE的蛋白酶抑制剂，通过阻止CPP32转化为其活性形式来抑制细胞凋亡。

Cyclopamine是一种天然存在的Hedgehog (Hh)特异性小分子信号甾体生物碱抑制剂，对肿瘤生长具有深远的抑制作用，在人乳腺癌细胞中具有显著的抗侵袭、抗增殖和抗雌激素活性。

MG-132是一种强效、可逆和细胞渗透的蛋白酶体抑制剂，属于合成肽醛类。

L-Kynurenine是L-色氨酸的代谢物，也是一种芳香烃受体 (aryl hydrocarbon receptor; AhR) 激动剂。

顺铂是最好的、最早的基于金属的化疗药物之一，用于治疗广泛的实体癌症，如睾丸癌、卵巢癌、膀胱癌、肺癌、宫颈癌、头颈部肿瘤和胃癌等。

Binds Hsp90 and GRP94, inhibits growth of cancer cells

Glycyrrhetinic acid is a triterpenoid aglycone component of the natural product glycyrrhizinic acid and possesses remarkable anti-proliferative and apoptosis-inducing activity in various cancer cell lines.

N6F11 is a novel, selective and potent inducer of iron death with anticancer and antitumour activity that promotes GPX4 degradation by binding to TRIM25 in cancer cells.

A furanocoumarin with anti-cancer activity

Hinokiflavone, isolated from Selaginella P. Beauv, Juniperus phoenicea and Rhus succedanea, possesses excellent pharmacological activities, including anti-inflammatory, antioxidant and antitumor activity. Hinokiflavone induces apoptosis and inhibits migration of breast cancer cells via EMT signalling pathway.

Chonglou Saponin VII (Dioscinin, Polyphyllin-VII, Paris saponin-VII), a kind of steroidal saponins from Chonglou (Rhizoma Paridis Chonglou), inhibits EMT and reduces the invasion of ovarian cancer cells via the GSK-3β/β-catenin signaling pathway.

A lipid decomposition product with cancer inhibiting activity

Caspase-3 inhibitor,cell-permeable

A mast cell tryptase inhibitor

Isoliquiritin apioside (ISLA, ILA), a component isolated from Glycyrrhizae radix rhizome (GR), significantly decreases PMA-induced increases in matrix metalloproteinase (MMP) activities and suppresses PMA-induced activation of mitogen-activated protein kinase (MAPK) and NF-κB. Isoliquiritin apioside possesses anti-metastatic and anti-angiogenic abilities in malignant cancer cells and ECs, with no cytotoxicity.