关于 "Cell Cycle/Checkpoint" 的结果9+ 个结果
筛选:PLK×
- BI 2536CAS: 755038-02-9
BI 2536是一种双重Polo样激酶（PLK）/溴结构域抑制剂，在无细胞激酶实验中，BI 2536 对PLK1、PLK2和PLK3的半数抑制浓度（IC 50 ）值分别为0.83nM、3.5nM和9.0nM。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC13543 | Poloxin | 321688-88-4 | PLK | ||
An inhibitor of the Plk1 polo-box domain | |||||
| GC62174 | ON1231320 | 1312471-39-8 | Apoptosis | ||
ON1231320 (7ao), an arylsulfonyl pyrido-pyrimidinone, is a highly specific inhibitor of polo like kinase 2 (PLK2). It also blocks tumor cell cycle progression in the G2/M phase in mitosis and causes apoptosis. | |||||
| GC13928 | HMN-214 | 173529-46-9 | PLK | ||
A prodrug form of HMN-176 | |||||
| GC11621 | GW843682X | 660868-91-7 | PLK | ||
A reversible polo-like kinase inhibitor | |||||
| GC12335 | GSK461364 | 929095-18-1 | PLK | ||
A reversible inhibitor of Plk1 | |||||
| GC10163 | MLN0905 | 1228960-69-7 | PLK | ||
A Plk1 inhibitor | |||||
| GC13903 | Ro3280 | 1062243-51-9 | PLK | ||
A selective Plk1 inhibitor | |||||
| GC12450 | BI 2536 | 755038-02-9 | Epigenetic Reader Domain | ||
BI 2536是一种双重Polo样激酶（PLK）/溴结构域抑制剂，在无细胞激酶实验中，BI 2536 对PLK1、PLK2和PLK3的半数抑制浓度（IC50）值分别为0.83nM、3.5nM和9.0nM。 | |||||
| GC14358 | Rigosertib (ON-01910,Estybon) | 1225497-78-8 | PLK | ||
A potent inhibitor of Plk1 | |||||