关于 "Aurora Kinase" 的结果16+ 个结果
筛选:PI3K/Akt/mTOR Signaling×
- CenisertibCAS: 871357-89-0
Cenisertib (AS-703569) 是一种多激酶抑制剂，可抑制 Aurora-kinase-A/B，ABL1，AKT，STAT5, FLT3 的活性。 Cenisertib 通过抑制肿瘤肥大细胞 (MC) 中几种不同分子靶标的活性抑制其生长。 Cenisertib 抑制异种移植模型中胰腺癌，乳腺癌，结肠癌，卵巢癌和肺癌以及白血病的肿瘤生长。
- S6 Kinase Substrate Peptide 32
Measures the activity of kinases that phosphorylate ribosomal protein S6.
- Comprehensive Kinase Screening Library
For screening of a variety of kinase inhibitors
- PI3-Kinase α Inhibitor 2 (hydrochloride)CAS: 1188890-32-5
A PI3K p110α inhibitor
PI3K/Akt/mTOR Signaling - PF-AKT400 (AKT protein kinase inhibitor)CAS: 1004990-28-6
PF-AKT400（AKT 蛋白激酶抑制剂）是一种广泛选择性、强效、ATP 竞争性 Akt 抑制剂，对 PKBα 的选择性高出 900 倍； (IC50=0.5 nM) 比 PKA (IC50=450 nM)。
- LY 294002 hydrochlorideCAS: 934389-88-5
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC35651 | Cenisertib | 871357-89-0 | FLT3 | ||
Cenisertib (AS-703569) 是一种多激酶抑制剂，可抑制 Aurora-kinase-A/B，ABL1，AKT，STAT5, FLT3 的活性。 Cenisertib 通过抑制肿瘤肥大细胞 (MC) 中几种不同分子靶标的活性抑制其生长。 Cenisertib 抑制异种移植模型中胰腺癌，乳腺癌，结肠癌，卵巢癌和肺癌以及白血病的肿瘤生长。 | |||||
| GC16366 | AKT Kinase Inhibitor | 842148-40-7 | Akt | ||
AKT Kinase Inhibitor是一种具有抗肿瘤活性的Akt激酶抑制剂。 | |||||
| GC67700 | AKT Kinase Inhibitor hydrochloride | - | Akt | ||
AKT Kinase Inhibitor hydrochloride 是一种具有抗肿瘤活性的 Akt 抑制剂。 | |||||
| GP10104 | S6 Kinase Substrate Peptide 32 | - | S6 Kinase | ||
Measures the activity of kinases that phosphorylate ribosomal protein S6. | |||||
| GC44641 | PI3-Kinase α Inhibitor 2 | 371943-05-4 | PI3K/Akt/mTOR Signaling | ||
A PI3K p110α inhibitor | |||||
| GC46123 | Comprehensive Kinase Screening Library | - | Signaling Pathways | ||
For screening of a variety of kinase inhibitors | |||||
| GC44642 | PI3-Kinase α Inhibitor 2 (hydrochloride) | 1188890-32-5 | PI3K/Akt/mTOR Signaling | ||
A PI3K p110α inhibitor | |||||
| GC32892 | PF-AKT400 (AKT protein kinase inhibitor) | 1004990-28-6 | Akt | ||
PF-AKT400（AKT 蛋白激酶抑制剂）是一种广泛选择性、强效、ATP 竞争性 Akt 抑制剂，对 PKBα 的选择性高出 900 倍； (IC50=0.5 nM) 比 PKA (IC50=450 nM)。 | |||||
| GC43790 | GSK3 Inhibitor XIII | 404828-08-6 | GSK-3 | ||
An inhibitor of GSK3 | |||||
| GC14181 | TBCA | 934358-00-6 | CK2 | ||
An inhibitor of casein kinase 2 | |||||
| GC16960 | 4,5,6,7-Tetrabromobenzimidazole | 577779-57-8 | CK2 | ||
A selective inhibitor of CK2 | |||||
| GC17837 | DMAT | 749234-11-5 | Casein Kinase | ||
A cell-permeable inhibitor of CK2 | |||||
| GC50009 | LY 294002 hydrochloride | 934389-88-5 | Autophagy | ||
Prototypical PI 3-kinase inhibitor; also inhibits other kinases | |||||
| GC16157 | 740 Y-P | 1236188-16-1 | PI3K | ||
740 Y-P是一种PI3K激活剂，浓度为20μM 。 | |||||
| GC37522 | RGB-286638 | 784210-87-3 | JAK | ||
A multi-kinase inhibitor | |||||
| GC37523 | RGB-286638 free base | 784210-88-4 | JAK | ||
A multi-kinase inhibitor | |||||