关于 "Aurora Kinase" 的结果12+ 个结果
筛选:PDGFR×
- Tyrosine kinase-IN-1CAS: 705946-27-6
Tyrosinekinase-IN-1是多靶点的酪氨酸激酶抑制剂，抑制KDR，Flt-1，FGFR1和PDGFRα的IC50值分别为4，20，4，2nM。
- PDGFRα kinase inhibitor 1CAS: 2209053-93-8
PDGFRα kinase inhibitor 1 是一种高选择性 II 型 PDGFRα 激酶抑制剂，抑制 PDGFRα 和 PDGFRβ 的 IC50 分别为 132 nM 和 6115 nM。
PDGFR - ChiauranibCAS: 1256349-48-0
Chiauranib (CS2164) selectively inhibits multiple kinase targets aurora B kinase (AURKB), colony-stimulating factor 1 receptor (CSF1R), and vascular endothelial growth factor receptor (VEGFR)/platelet-derived growth factor receptor (PDGFR)/c-Kit , thereby inhibiting the rapid proliferation of tumor cells, enhancing the antitumor immunity, and inhibiting tumor angiogenesis, to achieve the anti-tumor efficacy.
- ENMD-2076 L-(+)-Tartaric acidCAS: 1291074-87-7
ENMD-2076 L-(+)-Tartaric acid 是一种多靶点激酶抑制剂，对 Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1 的 IC50 为 1.86、14、58.2、15.9、92.7、70.8、56.4 nM , FGFR2, Src, PDGFRα, 分别。
PDGFR
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC34026 | Tyrosine kinase-IN-1 | 705946-27-6 | FGFR | ||
Tyrosinekinase-IN-1是多靶点的酪氨酸激酶抑制剂，抑制KDR，Flt-1，FGFR1和PDGFRα的IC50值分别为4，20，4，2nM。 | |||||
| GC65366 | PDGFRα kinase inhibitor 1 | 2209053-93-8 | PDGFR | ||
PDGFRα kinase inhibitor 1 是一种高选择性 II 型 PDGFRα 激酶抑制剂，抑制 PDGFRα 和 PDGFRβ 的 IC50 分别为 132 nM 和 6115 nM。 | |||||
| GC44583 | PD 089828 | 179343-17-0 | PDGFR | ||
An inhibitor of EGFR, PDGFβ, FGF, and c-Src | |||||
| GC16499 | Sorafenib Tosylate | 475207-59-1 | Other Apoptosis | ||
A multi-kinase inhibitor | |||||
| GC62145 | Chiauranib | 1256349-48-0 | c-FMS | ||
Chiauranib (CS2164) selectively inhibits multiple kinase targets aurora B kinase (AURKB), colony-stimulating factor 1 receptor (CSF1R), and vascular endothelial growth factor receptor (VEGFR)/platelet-derived growth factor receptor (PDGFR)/c-Kit , thereby inhibiting the rapid proliferation of tumor cells, enhancing the antitumor immunity, and inhibiting tumor angiogenesis, to achieve the anti-tumor efficacy. | |||||
| GC14683 | Sunitinib malate | 341031-54-7 | Autophagy | ||
A multi-kinase inhibitor | |||||
| GC16327 | Pazopanib (GW-786034) | 444731-52-6 | Autophagy | ||
A multi-kinase inhibitor | |||||
| GC12145 | ENMD-2076 L-(+)-Tartaric acid | 1291074-87-7 | PDGFR | ||
ENMD-2076 L-(+)-Tartaric acid 是一种多靶点激酶抑制剂，对 Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1 的 IC50 为 1.86、14、58.2、15.9、92.7、70.8、56.4 nM , FGFR2, Src, PDGFRα, 分别。 | |||||
| GC17959 | AZD2932 | 883986-34-3 | c-Kit | ||
A multi-kinase inhibitor | |||||
| GC11763 | Telatinib (BAY 57-9352) | 332012-40-5 | PDGFR | ||
A multi-kinase inhibitor | |||||
| GC34159 | Ilorasertib (ABT-348) | 1227939-82-3 | RET | ||
A multi-kinase inhibitor | |||||
| GC38519 | Ilorasertib hydrochloride | 1847485-91-9 | VEGFR | ||
A multi-kinase inhibitor | |||||