关于 "Bile Acids & Microbiome" 的结果13+ 个结果
- Sinapinic acid (Sinapic acid)CAS: 530-59-6
A phenylpropanoid hydroxycinnamic acid with diverse biological activities
Other Apoptosis - Rotundic acidCAS: 20137-37-5
Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.RA induces cell cycle arrest, DNA damage, and apoptosis by modulating the AKT/mTOR and MAPK pathways.
Other Apoptosis - Kynurenic acidCAS: 492-27-3
Kynurenic acid 是一种内源性色氨酸代谢物，是一种针对 NMDA、谷氨酸、α7 烟碱乙酰胆碱受体的广谱拮抗剂。
Other Apoptosis - Asiatic acidCAS: 464-92-6
Asiatic acid是一种五环三萜类化合物，可抑制EGFR活性，对野生型EGFR和T790M/L858R EGFR的IC 50 值分别为0.035nM和0.348nM。
- Minodronic acidCAS: 180064-38-4
Minodronic acid (YM529, ONO-5920) is a third-generation nitrogen-cotaining bisphosphonate that is used for the treatment of osteoporosis. Minodronic acid is an aminobisphosphonate that is a selective antagonist of purinergic P2X2/3 receptors involved in pain.
Other Apoptosis - Ursonic acidCAS: 6246-46-4
Ursonic acid (Prunol, Malol, beta-Ursolic acid, NSC4060, CCRIS 7123, TOS-BB-0966), present in many plants, is a pentacyclic triterpenoid that can be used as a cosmetics additive and serve as a starting material for synthesis of more potent bioactive derivatives, such as experimental antitumor agents. Ursonic acid induces the apoptosis of human cancer cells through multiple signaling pathways.
Other Apoptosis
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC31511 | Sinapinic acid (Sinapic acid) | 530-59-6 | Other Apoptosis | ||
A phenylpropanoid hydroxycinnamic acid with diverse biological activities | |||||
| GC38609 | Rotundic acid | 20137-37-5 | Other Apoptosis | ||
Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.RA induces cell cycle arrest, DNA damage, and apoptosis by modulating the AKT/mTOR and MAPK pathways. | |||||
| GC15880 | Penicillic Acid | 90-65-3 | Other Apoptosis | ||
A mycotoxin that inhibits quorum sensing | |||||
| GC38392 | Euscaphic acid | 53155-25-2 | Other Apoptosis | ||
A triterpene with diverse biological activities | |||||
| GC30110 | Oleic acid (9-cis-Octadecenoic acid) | 112-80-1 | Endogenous Metabolite | ||
油酸（9-顺式-十八碳烯酸）是一种单不饱和的Omega-9脂肪酸，存在于植物和动物中。 | |||||
| GC14533 | Kynurenic acid | 492-27-3 | Other Apoptosis | ||
Kynurenic acid 是一种内源性色氨酸代谢物，是一种针对 NMDA、谷氨酸、α7 烟碱乙酰胆碱受体的广谱拮抗剂。 | |||||
| GC11459 | Xanthurenic acid | 59-00-7 | mGluR | ||
Xanthurenic acid是一种内源性II组代谢型谷氨酸受体激动剂，参与丘脑的感觉传递。 | |||||
| GN10702 | Asiatic acid | 464-92-6 | Parasite | ||
Asiatic acid是一种五环三萜类化合物，可抑制EGFR活性，对野生型EGFR和T790M/L858R EGFR的IC50值分别为0.035nM和0.348nM。 | |||||
| GC36613 | Minodronic acid | 180064-38-4 | Other Apoptosis | ||
Minodronic acid (YM529, ONO-5920) is a third-generation nitrogen-cotaining bisphosphonate that is used for the treatment of osteoporosis. Minodronic acid is an aminobisphosphonate that is a selective antagonist of purinergic P2X2/3 receptors involved in pain. | |||||
| GC37873 | Ursonic acid | 6246-46-4 | Other Apoptosis | ||
Ursonic acid (Prunol, Malol, beta-Ursolic acid, NSC4060, CCRIS 7123, TOS-BB-0966), present in many plants, is a pentacyclic triterpenoid that can be used as a cosmetics additive and serve as a starting material for synthesis of more potent bioactive derivatives, such as experimental antitumor agents. Ursonic acid induces the apoptosis of human cancer cells through multiple signaling pathways. | |||||
| GC10480 | Betulinic acid | 472-15-1 | NF-κB | ||
白桦脂酸（Betulinic acid）是一种天然的五环三萜类化合物，是真核细胞拓扑异构酶I的抑制剂，IC50值为5μM。 | |||||
| GC17057 | Lithocholic Acid | 434-13-9 | Endogenous Metabolite | ||
A toxic secondary bile acid | |||||
| GC14273 | TTNPB (Arotinoid Acid) | 71441-28-6 | Autophagy | ||
A potent, selective RAR agonist | |||||