关于 "Aldehyde Dehydrogenase (ALDH)" 的结果32+ 个结果
- Betaine Aldehyde (chloride)CAS: 7758-31-8
An intermediate in the oxidation of choline to betaine
Metabolism - PKUMDL WQ 2101CAS: 304481-72-9
Negative allosteric modulator of 3-phosphoglycerate dehydrogenase (PHGDH)
- PKUMDL WQ 2201CAS: 592474-91-4
Negative allosteric modulator of 3-Phosphoglycerate dehydrogenase (PHGDH)
- AG-120 (racemic)CAS: 1448346-63-1
AG-120 (racemic), the racemic mixture of AG-120, is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity.
- GSK 2837808ACAS: 1445879-21-9
GSK2837808A 是一种选择性的 LDHA (lactate dehydrogenase A) 的抑制剂,对hLDHA和hLDHB的IC50分别为2.6 nM和43 nM.GSK2837808A(10 µM;24-72h)通过促进有氧糖酵解、增殖、细胞周期和细胞凋亡抵抗,阻断了着丝粒蛋白N (CENP-N)过表达对鼻咽癌细胞的影响。
- Ethyl potassium malonateCAS: 6148-64-7
Ethyl potassium malonate (Potassium 3-ethoxy-3-oxopropanoate) is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate.
- 6-AminonicotinamideCAS: 329-89-5
6-Aminonicotinamide是一种有效的烟酰胺抗代谢物，是竞争性 NADP+ 依赖性酶葡萄糖-6-磷酸脱氢酶 (G6PD) 的抑制剂(K i =0.46μM)。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC42926 | Betaine Aldehyde (chloride) | 7758-31-8 | Metabolism | ||
An intermediate in the oxidation of choline to betaine | |||||
| GC17293 | PHGDH-inactive | 1914971-16-6 | Dehydrogenase | ||
A negative control for NCT-502 and NCT-503 | |||||
| GC13760 | TC HSD 21 | 330203-01-5 | Others | ||
An inhibitor of 17β-HSD3 | |||||
| GC60763 | DHODH-IN-11 | 1263303-95-2 | Dihydroorotate Dehydrogenase | ||
A derivative of leflunomide | |||||
| GC10801 | Disulfiram | 97-77-8 | Interleukin Related | ||
An irreversible inhibitor of aldehyde dehydrogenase | |||||
| GC16816 | Galloflavin | 568-80-9 | Dehydrogenase | ||
An inhibitor of lactate dehydrogenase | |||||
| GC14783 | Trilostane | 13647-35-3 | Others | ||
A 3β-hydroxysteroid dehydrogenase inhibitor | |||||
| GC18496 | Leelamine (hydrochloride) | 16496-99-4 | Fatty Acid Synthase (FASN) | ||
An inhibitor of pyruvate dehydrogenase kinase | |||||
| GC17914 | Fomepizole | 7554-65-6 | Others | ||
An alcohol dehydrogenase inhibitor | |||||
| GC44048 | Leelamine | 1446-61-3 | Metabolism | ||
An inhibitor of pyruvate dehydrogenase kinase | |||||
| GC50508 | PKUMDL WQ 2101 | 304481-72-9 | Dehydrogenase | ||
Negative allosteric modulator of 3-phosphoglycerate dehydrogenase (PHGDH) | |||||
| GC50509 | PKUMDL WQ 2201 | 592474-91-4 | Dehydrogenase | ||
Negative allosteric modulator of 3-Phosphoglycerate dehydrogenase (PHGDH) | |||||
| GC10438 | WIN 18446 | 1477-57-2 | Dehydrogenase | ||
WIN 18446 (Fertilysin)是乙醛脱氢酶1A2(ALDH1A2)的有效抑制剂，IC50值为0.3μM。 | |||||
| GC10902 | CVT 10216 | 1005334-57-5 | Aldehyde Dehydrogenase (ALDH) | ||
A selective, reversible ALDH2 inhibitor | |||||
| GC10016 | NCT-501 | 1802088-50-1 | Aldehyde Dehydrogenase (ALDH) | ||
A reversible inhibitor of ALDH1A1 | |||||
| GC14921 | CPI-613 (Devimistat) | 95809-78-2 | Other Apoptosis | ||
An inhibitor of α-ketoglutarate dehydrogenase | |||||
| GC25039 | AG-120 (racemic) | 1448346-63-1 | Dehydrogenase | ||
AG-120 (racemic), the racemic mixture of AG-120, is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity. | |||||
| GC13464 | GSK 2837808A | 1445879-21-9 | Lactate Dehydrogenase | ||
GSK2837808A 是一种选择性的 LDHA (lactate dehydrogenase A) 的抑制剂,对hLDHA和hLDHB的IC50分别为2.6 nM和43 nM.GSK2837808A(10 µM;24-72h)通过促进有氧糖酵解、增殖、细胞周期和细胞凋亡抵抗,阻断了着丝粒蛋白N (CENP-N)过表达对鼻咽癌细胞的影响。 | |||||
| GC25389 | Ethyl potassium malonate | 6148-64-7 | Dehydrogenase | ||
Ethyl potassium malonate (Potassium 3-ethoxy-3-oxopropanoate) is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate. | |||||
| GC10531 | AGI-5198 | 1355326-35-0 | Isocitrate Dehydrogenase (IDH) | ||
A potent, selective inhibitor of IDH1 mutations | |||||
| GC14757 | AGI-6780 | 1432660-47-3 | Isocitrate Dehydrogenase (IDH) | ||
A potent, selective inhibitor of mutant IDH2 | |||||
| GC10462 | 6-Aminonicotinamide | 329-89-5 | Dehydrogenase | ||
6-Aminonicotinamide是一种有效的烟酰胺抗代谢物，是竞争性 NADP+ 依赖性酶葡萄糖-6-磷酸脱氢酶 (G6PD) 的抑制剂(Ki=0.46μM)。 | |||||
| GC13262 | A-771726 | 163451-81-8 | Dehydrogenase | ||
An active metabolite of leflunomide | |||||
| GC17467 | Gimeracil | 103766-25-2 | Others | ||
A DYPD inhibitor | |||||