关于 "Nucleoside Antimetabolite/Analogue" 的结果2+ 个结果

筛选:JAK/STAT Signaling×
  • GC17222 structure
    GLPG0634 analogue
    CAS: 1206101-20-3

    GLPG0634 类似物 (Compoun 176) 是一种广谱 JAK 抑制剂,对 JAK1、JAK2 和 JAK3 的 IC50 值 <100 nM。

  • GC25899 structure
    SC-1
    CAS: 1313019-65-6

    SC-1 (1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea, STAT3-IN-7), a Sorafenib analogue and potently inhibits the phosphorylation of STAT3, induces cell apoptosis through SHP-1 dependent STAT3 inactivation.