关于 "Aryl Hydrocarbon Receptor" 的结果25+ 个结果
- GNF351CAS: 1227634-69-6
GNF351 is a potent antagonist of aryl hydrocarbon receptor (AHR). GNF351 interacts directly with the AHR ligand binding pocket and competes with a well-characterized photoaffinity AHR ligand for binding to the AHR with IC50 of 62 nM.
- Carbidopa (hydrate)CAS: 38821-49-7
Carbidopa (hydrate)是一种aryl hydrocarbon receptor (AhR)激动剂，可抑制胰腺癌细胞和肿瘤的生长。
- L-Kynurenine-d4-1CAS: 194546-33-3
L-Kynurenine-d4-1 是 L-Kynurenine 氘代物。L-Kynurenine是L-色氨酸的代谢物。它是一种芳香烃受体 (aryl hydrocarbon receptor) 激动剂。
- Skatole-d3CAS: 111399-60-1
Skatole-d3 是 Skatole 的氘代物。Skatole 是肠道菌群产生的物质，通过激活芳基烃受体 (aryl hydrocarbon receptors) 和 p38 调节肠上皮细胞功能。
- Tapinarof (WBI 1001)CAS: 79338-84-4
Tapinarof (GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505) is a natural agonist of aryl hydrocarbon receptor (AhR) and induces nuclear translocation of AhR in immortalized keratinocytes (HaCaT) with EC50 of 0.16 nM. Tapinarof induces cellular apoptosis in CD4+ T cells in a dosedependent manner with IC50 of 5.2 μM.
- EP4 Receptor Antagonist 1CAS: 2287259-07-6
EP4 receptor antagonist 1前列腺素E2受体EP4亚型的高效选择性拮抗剂，对人和小鼠EP4受体的半抑制浓度（IC₅₀）分别为6.1nM和16.2nM。
Immunology/Inflammation - Glucocorticoid receptor modulator 1CAS: 2868357-11-1
Glucocorticoid receptor modulator 1是一种口服活性非甾体选择性糖皮质激素受体调节剂，对NF-κB和AP-1的IC50值分别为9 nM和130 nM。
- IFN-α Receptor Recognition Peptide 1CAS: 153840-64-3
IFN-α Receptor Recognition Peptide 1 是 IFN-α 的一个多肽序列，为 IFN-α 受体识别肽。
- (Ala1)-PAR4 (1-6) amide (mouse) (trifluoroacetate salt)
A peptide agonist of PAR4
Immunology/Inflammation - Telratolimod (MEDI 9197)CAS: 1359993-59-1
Telratolimod (MEDI 9197)是一种有效的toll-like receptor 7（TLR-7）和toll-like receptor 8（TLR-8）的激动剂。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC12040 | L-Kynurenine | 2922-83-0 | Endogenous Metabolite | ||
L-Kynurenine是L-色氨酸的代谢物，也是一种芳香烃受体 (aryl hydrocarbon receptor; AhR) 激动剂。 | |||||
| GC11817 | PDM 2 | 688348-25-6 | Aryl Hydrocarbon Receptor | ||
A resveratrol-based aryl hydrocarbon receptor antagonist | |||||
| GC18824 | CAY10465 | 688348-33-6 | Aryl Hydrocarbon Receptor | ||
A resveratrol-based aryl hydrocarbon receptor agonist | |||||
| GC50422 | 10-Cl-BBQ | 23982-76-5 | Aryl Hydrocarbon Receptor | ||
Potent aryl hydrocarbon receptor (AhR) agonist; orally bioavailable | |||||
| GC34597 | GNF351 | 1227634-69-6 | Aryl Hydrocarbon Receptor | ||
GNF351 is a potent antagonist of aryl hydrocarbon receptor (AHR). GNF351 interacts directly with the AHR ligand binding pocket and competes with a well-characterized photoaffinity AHR ligand for binding to the AHR with IC50 of 62 nM. | |||||
| GC47037 | Carbidopa (hydrate) | 38821-49-7 | Aryl Hydrocarbon Receptor | ||
Carbidopa (hydrate)是一种aryl hydrocarbon receptor (AhR)激动剂，可抑制胰腺癌细胞和肿瘤的生长。 | |||||
| GC64898 | L-Kynurenine-d4-1 | 194546-33-3 | Aryl Hydrocarbon Receptor | ||
L-Kynurenine-d4-1 是 L-Kynurenine 氘代物。L-Kynurenine是L-色氨酸的代谢物。它是一种芳香烃受体 (aryl hydrocarbon receptor) 激动剂。 | |||||
| GC69908 | Skatole-d3 | 111399-60-1 | Aryl Hydrocarbon Receptor | ||
Skatole-d3 是 Skatole 的氘代物。Skatole 是肠道菌群产生的物质，通过激活芳基烃受体 (aryl hydrocarbon receptors) 和 p38 调节肠上皮细胞功能。 | |||||
| GC31732 | Tapinarof (WBI 1001) | 79338-84-4 | Aryl Hydrocarbon Receptor | ||
Tapinarof (GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505) is a natural agonist of aryl hydrocarbon receptor (AhR) and induces nuclear translocation of AhR in immortalized keratinocytes (HaCaT) with EC50 of 0.16 nM. Tapinarof induces cellular apoptosis in CD4+ T cells in a dosedependent manner with IC50 of 5.2 μM. | |||||
| GC32019 | Interferon receptor agonist | 2215120-36-6 | IFNAR | ||
干扰素受体激动剂（化合物 6）是一种干扰素 (IFN) 受体诱导剂。 | |||||
| GC39554 | AT2 receptor agonist C21 | 477775-14-7 | Cardiomyopathy | ||
An AT2 receptor agonist | |||||
| GC17996 | Toll-like receptor modulator | 926927-42-6 | TLR | ||
Toll 样受体调节剂是调节免疫功能的 TLR7/8 调节剂。 | |||||
| GC47297 | EP4 Receptor Antagonist 1 | 2287259-07-6 | Immunology/Inflammation | ||
EP4 receptor antagonist 1前列腺素E2受体EP4亚型的高效选择性拮抗剂，对人和小鼠EP4受体的半抑制浓度（IC₅₀）分别为6.1nM和16.2nM。 | |||||
| GC71181 | Glucocorticoid receptor modulator 1 | 2868357-11-1 | AP-1 | ||
Glucocorticoid receptor modulator 1是一种口服活性非甾体选择性糖皮质激素受体调节剂，对NF-κB和AP-1的IC50值分别为9 nM和130 nM。 | |||||
| GC45063 | Toll-Like Receptor 7 Ligand II | 226907-52-4 | Hepatitis | ||
A TLR7 agonist | |||||
| GC36296 | IFN-α Receptor Recognition Peptide 1 | 153840-64-3 | Peptides | ||
IFN-α Receptor Recognition Peptide 1 是 IFN-α 的一个多肽序列，为 IFN-α 受体识别肽。 | |||||
| GC40159 | PAR1 (1-6) (mouse, rat) (trifluoroacetate salt) | - | Innate Immunity | ||
A peptide agonist of PAR1 | |||||
| GC52436 | TRAP-6 amide (trifluoroacetate salt) | - | Immunology/Inflammation | ||
A peptide PAR1 agonist | |||||
| GC41697 | (Ala1)-PAR4 (1-6) amide (mouse) (trifluoroacetate salt) | - | Immunology/Inflammation | ||
A peptide agonist of PAR4 | |||||
| GC36043 | FICZ | 172922-91-7 | Aryl Hydrocarbon Receptor | ||
FICZ（甲酰吲哚 咔唑）作为芳基烃受体 (AhR) 的内源性配体，可以发挥多效性作用，包括防止炎症、纤维化和氧化应激。 | |||||
| GC40775 | Dexamethasone | 50-02-2 | Complement System | ||
地塞米松是糖皮质激素家族的一员，可以保护软骨结构和功能免受关节炎相关变化的影响，包括基质丢失、炎症和软骨活力。 | |||||
| GC44999 | Tauro-α-muricholic Acid (sodium salt) | 2260905-08-4 | FXR & LXR | ||
An FXR receptor antagonist | |||||
| GC33076 | Telratolimod (MEDI 9197) | 1359993-59-1 | TLR | ||
Telratolimod (MEDI 9197)是一种有效的toll-like receptor 7（TLR-7）和toll-like receptor 8（TLR-8）的激动剂。 | |||||
| GC44023 | L-902688 | 634193-54-7 | Cyclooxygenase | ||
A selective EP4 receptor agonist | |||||