关于 "Histone Acetyltransferases" 的结果22 个结果
筛选:Histone Methyltransferase×
- Histone H3 Peptide Substrate (1-21)
Target substrate for several histone modifying enzymes
- EZM0414 (SETD2-IN-1)CAS: 2411748-50-8
EZM0414 is a potent, selective, and orally bioavailable inhibitor of Histone-lysine N-methyltransferase SETD2.
Histone Methyltransferase - AMI-1 free acidCAS: 134-47-4
AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 μM and 8.8 μM for yeast Hmt1p and human PRMT1, respectively.
Histone Methyltransferase - EntacaponeCAS: 130929-57-6
Entacapone是一种有效的、可逆的、外周作用和具有口服活性的儿茶酚-O-甲基转移酶（COMT）抑制剂，可有效抑制大鼠肝脏总COMT，IC 50 和K i 值分别为20.1nM和10.7nM。
- 3-Deazaneplanocin A (DZNep) hydrochlorideCAS: 120964-45-6
3-Deazaneplanocin A (DZNep) hydrochloride 是一种腺苷类似物，是一种竞争性 S-腺苷高半胱氨酸水解酶抑制剂，在无细胞试验中的 Ki 为 50 pM。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GP10020 | Histone-H2A-(107-122)-Ac-OH | - | Histone Methyltransferase | ||
Histone-H2A peptide | |||||
| GC43837 | Histone H3 Peptide Substrate (1-21) | - | Histone Acetyltransferases | ||
Target substrate for several histone modifying enzymes | |||||
| GC42944 | BIX01294 (hydrochloride hydrate) | 1808255-64-2 | Stem Cell | ||
An inhibitor of G9a histone methyltransferase | |||||
| GC37856 | UNC0321 | 1238673-32-9 | Histone Methyltransferase | ||
A highly potent inhibitor of G9a histone methyltransferase | |||||
| GC14062 | EPZ-6438 | 1403254-99-8 | Histone Methyltransferase | ||
EPZ-6438 是一种有效且具有生物利用度的 EZH2 抑制剂，EZH2 是多梳抑制复合物 2 (PRC2) 的催化亚基，可催化组蛋白 H3 (H3K27) 的赖氨酸 27 甲基化，从而抑制含有人 PRC2 的活性抑制常数 Ki 值为 2.5 nM 的野生型 EZH2。 | |||||
| GC14249 | UNC 0642 | 1481677-78-4 | Sigma Receptor | ||
A G9a histone methyltransferase inhibitor | |||||
| GC15688 | UNC 0224 | 1197196-48-7 | Histone Methyltransferase | ||
A potent inhibitor of G9a histone methyltransferase | |||||
| GC64900 | EZM0414 (SETD2-IN-1) | 2411748-50-8 | Histone Methyltransferase | ||
EZM0414 is a potent, selective, and orally bioavailable inhibitor of Histone-lysine N-methyltransferase SETD2. | |||||
| GC12171 | BIX 01294 | 935693-62-2 | Autophagy | ||
An inhibitor of G9a histone methyltransferase | |||||
| GC15610 | UNC0638 | 1255580-76-7 | Autophagy | ||
A G9a and GLP histone methyltransferase inhibitor | |||||
| GC39840 | AMI-1 free acid | 134-47-4 | Histone Methyltransferase | ||
AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 μM and 8.8 μM for yeast Hmt1p and human PRMT1, respectively. | |||||
| GC17334 | Entacapone | 130929-57-6 | COMT | ||
Entacapone是一种有效的、可逆的、外周作用和具有口服活性的儿茶酚-O-甲基转移酶（COMT）抑制剂，可有效抑制大鼠肝脏总COMT，IC50和Ki值分别为20.1nM和10.7nM。 | |||||
| GC11340 | (R)-PFI 2 hydrochloride | 1627607-87-7 | Histone Methyltransferase | ||
A SET7/9 inhibitor | |||||
| GC16015 | A 366 | 1527503-11-2 | Histone Methyltransferase | ||
A 366是一种选择性的G9a/GLP组蛋白甲基转移酶抑制剂，可抑制G9a（IC50=3.3nM）和GLP（IC50=38nM）的活性。 | |||||
| GC11491 | SGC 0946 | 1561178-17-3 | Histone Methyltransferase | ||
A potent inhibitor of DOT1L | |||||
| GC13878 | EPZ005687 | 1396772-26-1 | EZH2 | ||
A potent, selective inhibitor of EZH2 | |||||
| GC12932 | EPZ5676 | 1380288-87-8 | Histone Methyltransferase | ||
EPZ5676是一种新型的、高效的、选择性DOT1L组蛋白甲基转移酶抑制剂，Ki值小于80pM，对DOT1L的IC50为0.8nM，选择性比作用于其他多种蛋白甲基转移酶高37000倍。 | |||||
| GC14936 | Chaetocin | 28097-03-2 | Histone Methyltransferase | ||
据报道毛壳素是组蛋白甲基转移酶 (HMT)（例如 SUV39H1）的非特异性抑制剂，从而影响基因表达。 | |||||
| GC13145 | 3-Deazaneplanocin,DZNep | 102052-95-9 | EZH2 | ||
An inhibitor of lysine methyltransferase EZH2 | |||||
| GC16518 | UNC 0646 | 1320288-17-2 | Histone Methyltransferase | ||
An inhibitor of G9a/GLP methyltransferases | |||||
| GC13383 | EPZ004777 | 1338466-77-5 | Other Apoptosis | ||
EPZ004777 作为一种有效的表观遗传调节剂，可以逆转 TGF-β1 诱导的 T 调节细胞，可用于治疗多种免疫疾病。 | |||||
| GC17907 | 3-Deazaneplanocin A (DZNep) hydrochloride | 120964-45-6 | EZH2 | ||
3-Deazaneplanocin A (DZNep) hydrochloride 是一种腺苷类似物，是一种竞争性 S-腺苷高半胱氨酸水解酶抑制剂，在无细胞试验中的 Ki 为 50 pM。 | |||||