关于 "Bromodomain" 的结果6 个结果
筛选:Histone Acetyltransferases×
- PF-CBP1 hydrochlorideCAS: 2070014-93-4
An inhibitor of the CBP and p300 bromodomains
Histone Acetyltransferases - GNE-781CAS: 1936422-33-1
GNE-781 (compound 19) is an orally active, highly potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP) with IC50 of 0.94 nM in TR-FRET assay. GNE-781 also inhibits BRET and BRD4(1) with IC50 of 6.2 nM and 5100 nM, respectively. GNE-781 exhibits antitumor activity.
Histone Acetyltransferases
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC10174 | SGC-CBP30 | 1613695-14-9 | Histone Acetyltransferases | ||
A potent inhibitor of CREBBP/EP300 bromodomains | |||||
| GC10382 | CPI-637 | 1884712-47-3 | Histone Acetyltransferases | ||
An inhibitor of CBP/EP300 bromodomains | |||||
| GC36887 | PF-CBP1 hydrochloride | 2070014-93-4 | Histone Acetyltransferases | ||
An inhibitor of the CBP and p300 bromodomains | |||||
| GC45503 | L-Moses (hydrochloride) | - | Histone Acetyltransferases | ||
A PCAF bromodomain inhibitor | |||||
| GC31731 | GSK 4027 | 2079896-25-4 | Histone Acetyltransferases | ||
A PCAF/GCN5 bromodomain inhibitor | |||||
| GC32081 | GNE-781 | 1936422-33-1 | Histone Acetyltransferases | ||
GNE-781 (compound 19) is an orally active, highly potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP) with IC50 of 0.94 nM in TR-FRET assay. GNE-781 also inhibits BRET and BRD4(1) with IC50 of 6.2 nM and 5100 nM, respectively. GNE-781 exhibits antitumor activity. | |||||