关于 "Oxidative Phosphorylation" 的结果13+ 个结果
- Brexpiprazole S-oxideCAS: 1191900-51-2
BrexpiprazoleS-oxide(DM-3411)是Brexpiprazole的主要代谢产物，并通过细胞色素P4503A4(CYP3A4)代谢。Brexpiprazole是一种非典型抗精神病药，是人5-HT1A和多巴胺受体的部分激动剂，Ki分别为0.12nM和0.3nM。Brexpiprazole也是5-HT2A受体的拮抗剂，Ki为0.47nM。
- Scopolamine N-oxide hydrobromide (Hyoscine N-oxide hydrobromide)CAS: 6106-81-6
Scopolamine N-Oxide (Hyoscine N-oxide, Genoscopolamine) is a muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors.
- Clozapine N-oxide (CNO)CAS: 34233-69-7
Clozapine N-oxide（CNO）是一种强效的多巴胺拮抗剂，也是一种选择性肌动蛋白M4受体（EC50=11 nM）激动剂。
- Brexpiprazole S-oxide-d8CAS: 2748605-29-8
Brexpiprazole S-oxide-d8 是 Brexpiprazole S-oxide 的氘代物。Brexpiprazole S-oxide 是 Brexpiprazole 的主要代谢产物，并通过细胞色素 P450 3A4 (CYP3A4) 代谢。Brexpiprazole 是一种非典型抗精神病药，是人 5-HT1A 和多巴胺受体的部分激动剂，Ki 分别为 0.12 nM 和 0.3 nM。Brexpiprazole 也是 5-HT2A 受体的拮抗剂，Ki 为 0.47 nM。
- NLX-204 hydrochloride
NLX-204 is a potent, selective agonist of ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor with pKi of 10.19.
- HigenamineCAS: 5843-65-2
Demethyl-Coclaurine (Higenamine, Norcoclaurine), the key component of the Chinese herb aconite root, is a beta-2 adrenergic receptor (β2-AR) agonist. Demethyl-Coclaurine stimulates AKT phosphorylation and requires PI3K activation for the anti-apoptotic effect in cardiomyocytes.
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC60662 | Brexpiprazole S-oxide | 1191900-51-2 | Dopamine Receptor | ||
BrexpiprazoleS-oxide(DM-3411)是Brexpiprazole的主要代谢产物，并通过细胞色素P4503A4(CYP3A4)代谢。Brexpiprazole是一种非典型抗精神病药，是人5-HT1A和多巴胺受体的部分激动剂，Ki分别为0.12nM和0.3nM。Brexpiprazole也是5-HT2A受体的拮抗剂，Ki为0.47nM。 | |||||
| GC49511 | Nicorandil N-oxide | 107833-98-7 | Membrane Transporter/Ion Channel | ||
A metabolite of nicorandil | |||||
| GC30901 | Scopolamine N-oxide hydrobromide (Hyoscine N-oxide hydrobromide) | 6106-81-6 | mAChR | ||
Scopolamine N-Oxide (Hyoscine N-oxide, Genoscopolamine) is a muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors. | |||||
| GC10822 | Clozapine N-oxide (CNO) | 34233-69-7 | Drug Metabolite | ||
Clozapine N-oxide（CNO）是一种强效的多巴胺拮抗剂，也是一种选择性肌动蛋白M4受体（EC50=11 nM）激动剂。 | |||||
| GC36737 | Nicotinamide N-oxide | 1986-81-8 | Endogenous Metabolite | ||
A metabolite of nicotinamide | |||||
| GC68806 | Brexpiprazole S-oxide-d8 | 2748605-29-8 | 5-HT Receptor | ||
Brexpiprazole S-oxide-d8 是 Brexpiprazole S-oxide 的氘代物。Brexpiprazole S-oxide 是 Brexpiprazole 的主要代谢产物，并通过细胞色素 P450 3A4 (CYP3A4) 代谢。Brexpiprazole 是一种非典型抗精神病药，是人 5-HT1A 和多巴胺受体的部分激动剂，Ki 分别为 0.12 nM 和 0.3 nM。Brexpiprazole 也是 5-HT2A 受体的拮抗剂，Ki 为 0.47 nM。 | |||||
| GC10826 | PIT | 56583-49-4 | P2Y Receptor | ||
Purinergic P2Y receptor ligand | |||||
| GC13597 | Pyrrolidino PAF C-16 | 91021-63-5 | PAF Receptors | ||
A potent analog of PAF C-16 | |||||
| GC13752 | Hexanolamino PAF C-16 | 137566-83-7 | PAF Receptors | ||
A PAF analog | |||||
| GC13155 | MRS 2693 trisodium salt | 1448858-83-0 | P2Y Receptor | ||
P2Y6 agonist | |||||
| GC13588 | 5-OMe-UDP trisodium salt | 1207530-98-0 | P2Y Receptor | ||
Potent P2Y6 agonist | |||||
| GC63111 | NLX-204 hydrochloride | - | 5-HT Receptor | ||
NLX-204 is a potent, selective agonist of ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor with pKi of 10.19. | |||||
| GC38099 | Higenamine | 5843-65-2 | Other Apoptosis | ||
Demethyl-Coclaurine (Higenamine, Norcoclaurine), the key component of the Chinese herb aconite root, is a beta-2 adrenergic receptor (β2-AR) agonist. Demethyl-Coclaurine stimulates AKT phosphorylation and requires PI3K activation for the anti-apoptotic effect in cardiomyocytes. | |||||