关于 "LPA Receptor" 的结果95+ 个结果
筛选:GPCR/G protein×
- Ki16425CAS: 355025-24-0
Ki16425是溶血磷脂酸受体 LPA1 和 LPA3 的拮抗剂，Ki 值分别为 0.25 和 0.36μM。Ki16425 可降低 LPA 诱导的 p42/p44 MAPK 的活化，阻断 LPA 诱导的是相关蛋白（YAP）和含 WW 结构域的转录调节蛋白 1（TAZ）的去磷酸化，从而抑制 Hippo 信号通路。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC36582 | Men 10376 TFA | - | Peptides | ||
An NK2 receptor antagonist | |||||
| GC65450 | CT1812 | 1802632-22-9 | Sigma Receptor | ||
CT1812 (Sigma-2 receptor antagonist 1) 是 sigma-2 (σ-2) 受体拮抗剂。 | |||||
| GC12362 | ONO-7300243 | 638132-34-0 | LPL Receptor | ||
An LPA1 receptor antagonist | |||||
| GC19078 | BMS-986020 | 1257213-50-5 | LPL Receptor | ||
An LPA1 receptor antagonist | |||||
| GC38470 | BMS-986020 sodium | 1380650-53-2 | LPL Receptor | ||
An LPA1 receptor antagonist | |||||
| GC15908 | AM-095 free base | 1228690-36-5 | LPL Receptor | ||
A selective LPA1 receptor antagonist | |||||
| GC13476 | AM966 | 1228690-19-4 | LPL Receptor | ||
A potent and selective LPA1 receptor antagonist | |||||
| GC13205 | U 46619 | 56985-40-1 | Prostaglandin Receptor | ||
A TP receptor agonist | |||||
| GC11343 | Propranolol HCl | 318-98-9 | Adrenergic Receptor | ||
A β-adrenergic receptor antagonist | |||||
| GC31904 | AS2717638 | 2148339-28-8 | LPL Receptor | ||
An LPA5 antagonist | |||||
| GC16558 | DBIBB | 1569309-92-7 | LPA Receptor | ||
A non-lipid agonist of LPA2 | |||||
| GC16937 | Carbamoylcholine chloride | 51-83-2 | nAChR | ||
Cholinergic receptor agonist | |||||
| GC17256 | Pilocarpine HCl | 54-71-7 | mAChR | ||
A muscarinic acetylcholine receptor agonist | |||||
| GC11714 | Prucalopride | 179474-81-8 | 5-HT Receptor | ||
A selective 5-HT4 receptor agonist | |||||
| GC17319 | L-Phenylephrine | 59-42-7 | Adrenergic Receptor | ||
A selective adrenergic α1A receptor agonist | |||||
| GC40775 | Dexamethasone | 50-02-2 | Complement System | ||
地塞米松是糖皮质激素家族的一员，可以保护软骨结构和功能免受关节炎相关变化的影响，包括基质丢失、炎症和软骨活力。 | |||||
| GC11374 | Ki16425 | 355025-24-0 | LPL Receptor | ||
Ki16425是溶血磷脂酸受体 LPA1 和 LPA3 的拮抗剂，Ki 值分别为 0.25 和 0.36μM。Ki16425 可降低 LPA 诱导的 p42/p44 MAPK 的活化，阻断 LPA 诱导的是相关蛋白（YAP）和含 WW 结构域的转录调节蛋白 1（TAZ）的去磷酸化，从而抑制 Hippo 信号通路。 | |||||
| GC12303 | Desmopressin | 16679-58-6 | Vasopressin Receptor | ||
A vasopressin receptor agonist | |||||
| GC11278 | Boc-MLF | 67247-12-5 | Formyl Peptide Receptors | ||
formyl peptide receptor 1 (FPR1) antagonist | |||||
| GC11316 | UCB 35625 | 301648-08-8 | Chemokine Receptors | ||
chemokine CCR1 and CCR3 receptor antagonist | |||||
| GC13371 | Fluticasone propionate | 80474-14-2 | Glucocorticoid Receptor | ||
A synthetic corticosteroid and glucocorticoid receptor agonist | |||||
| GC12197 | MK 571 | 115104-28-4 | Leukotriene Receptor | ||
A selective CysLT1 receptor antagonist | |||||
| GC11017 | ZM 241385 | 139180-30-6 | Adenosine Receptor | ||
An A2A adenosine receptor antagonist | |||||
| GC10219 | AF-DX 116 | 102394-31-0 | mAChR | ||
A muscarinic M2 receptor antagonist | |||||