关于 "Nuclear Receptors" 的结果2+ 个结果
筛选:Chromatin/Epigenetics×
- BI 9321CAS: 2387510-86-1
Nuclear receptor-binding SET domain (NSD) 3 antagonist; selectively binds PWWP1 domain
- AZD5153 6-Hydroxy-2-naphthoic acidCAS: 1869912-40-2
AZD-5153 6-hydroxy-2-naphthoic acid (HNT salt) is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor with pKi of 8.3 for BRD4. AZD-5153 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes. NSD3, via H3K36me2, acts as an epigenetic deregulator to facilitate the expression of oncogenesis-promoting genes.
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC50540 | BI 9321 | 2387510-86-1 | Histone Methyltransferase | ||
Nuclear receptor-binding SET domain (NSD) 3 antagonist; selectively binds PWWP1 domain | |||||
| GC35448 | AZD5153 6-Hydroxy-2-naphthoic acid | 1869912-40-2 | Epigenetic Reader Domain | ||
AZD-5153 6-hydroxy-2-naphthoic acid (HNT salt) is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor with pKi of 8.3 for BRD4. AZD-5153 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes. NSD3, via H3K36me2, acts as an epigenetic deregulator to facilitate the expression of oncogenesis-promoting genes. | |||||