关于 "Aurora Kinase" 的结果27+ 个结果
筛选:Cell Cycle/Checkpoint×
- Aurora Kinases-IN-3CAS: 2840558-83-8
Aurora Kinases-IN-3（化合物15a）是一种口服活性AURKB抑制剂，通过破坏AURKB的有丝分裂定位来引发AURKB抑制活性。
- AKI603CAS: 1432515-73-5
AKI-603 is an inhibitor of Aurora kinase A (AurA), which is developed to overcome resistance mediated by BCR-ABL-T315I mutation.
- CenisertibCAS: 871357-89-0
Cenisertib (AS-703569) 是一种多激酶抑制剂，可抑制 Aurora-kinase-A/B，ABL1，AKT，STAT5, FLT3 的活性。 Cenisertib 通过抑制肿瘤肥大细胞 (MC) 中几种不同分子靶标的活性抑制其生长。 Cenisertib 抑制异种移植模型中胰腺癌，乳腺癌，结肠癌，卵巢癌和肺癌以及白血病的肿瘤生长。
- Aurora B inhibitor 1CAS: 937276-52-3
AuroraBinhibitor1是一种AuroraB(Aurora-1)抑制剂，Ki值<0.010uM。详细信息请参考专利文献WO2007059299A1中的化合物1-3。
- Rho-Kinase-IN-2CAS: 2573071-18-6
Rho-Kinase-IN-2 (Compound 23) 是一种具有口服活性的、选择性的和中枢神经系统 (CNS) 渗透性的 Rho激酶 (ROCK) 抑制剂 (ROCK2 IC50=3 nM)。Rho-Kinase-IN-2 可用于亨廷顿病的研究。
- ATR kinase substrate peptide
ATR kinase substrate peptide（化合物45）是ATR（共济失调毛细血管扩张和Rad3相关）蛋白激酶（Ki=6 nM）的有效和选择性抑制剂。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC40667 | Aurora Kinase Inhibitor II | 331770-21-9 | Aurora Kinase | ||
Blocks Aurora A kinase activity | |||||
| GC73375 | Aurora Kinases-IN-3 | 2840558-83-8 | PLK | ||
Aurora Kinases-IN-3（化合物15a）是一种口服活性AURKB抑制剂，通过破坏AURKB的有丝分裂定位来引发AURKB抑制活性。 | |||||
| GC67899 | Aurora kinase inhibitor-8 | 2133001-88-2 | Aurora Kinase | ||
Aurora kinase inhibitor-8 是一种高选择性 Aurora 激酶的抑制剂。 | |||||
| GC10479 | PHA-680632 | 398493-79-3 | Aurora Kinase | ||
An Aurora kinase inhibitor | |||||
| GC13837 | SNS-314 Mesylate | 1146618-41-8 | Aurora Kinase | ||
A pan-Aurora kinase inhibitor | |||||
| GC19092 | CCT241736 | 1402709-93-6 | Aurora Kinase | ||
A dual inhibitor of Aurora kinases and FLT3 | |||||
| GC17828 | BI-847325 | 1207293-36-4 | Other Apoptosis | ||
A selective dual MEK/Aurora kinase inhibitor | |||||
| GC15106 | CYC116 | 693228-63-6 | Aurora Kinase | ||
A potent Aurora kinase inhibitor | |||||
| GC14566 | CCT137690 | 1095382-05-0 | Other Apoptosis | ||
An inhibitor of Aurora kinases and FLT3 | |||||
| GC11310 | CCT129202 | 942947-93-5 | Aurora Kinase | ||
An Aurora kinase inhibitor | |||||
| GC14955 | Barasertib (AZD1152-HQPA) | 722544-51-6 | Aurora Kinase | ||
A selective Aurora kinase B inhibitor | |||||
| GC13198 | AMG-900 | 945595-80-2 | Aurora Kinase | ||
A selective pan-Aurora kinase inhibitor | |||||
| GC62433 | AKI603 | 1432515-73-5 | Aurora Kinase | ||
AKI-603 is an inhibitor of Aurora kinase A (AurA), which is developed to overcome resistance mediated by BCR-ABL-T315I mutation. | |||||
| GC15217 | Danusertib (PHA-739358) | 827318-97-8 | Autophagy | ||
A pan-Aurora kinase and Abl inhibitor | |||||
| GC11085 | TAK-901 | 934541-31-8 | Aurora Kinase | ||
A non-selective inhibitor of Aurora kinases | |||||
| GC12612 | JNJ-7706621 | 443797-96-4 | CDK | ||
A dual inhibitor of CDKs and Aurora kinases | |||||
| GC35651 | Cenisertib | 871357-89-0 | FLT3 | ||
Cenisertib (AS-703569) 是一种多激酶抑制剂，可抑制 Aurora-kinase-A/B，ABL1，AKT，STAT5, FLT3 的活性。 Cenisertib 通过抑制肿瘤肥大细胞 (MC) 中几种不同分子靶标的活性抑制其生长。 Cenisertib 抑制异种移植模型中胰腺癌，乳腺癌，结肠癌，卵巢癌和肺癌以及白血病的肿瘤生长。 | |||||
| GC33379 | Aurora B inhibitor 1 | 937276-52-3 | Aurora Kinase | ||
AuroraBinhibitor1是一种AuroraB(Aurora-1)抑制剂，Ki值<0.010uM。详细信息请参考专利文献WO2007059299A1中的化合物1-3。 | |||||
| GC13332 | Aurora A Inhibitor I | 1158838-45-9 | Other Apoptosis | ||
A potent and selective inhibitor of Aurora A kinase | |||||
| GC66050 | Rho-Kinase-IN-2 | 2573071-18-6 | ROCK | ||
Rho-Kinase-IN-2 (Compound 23) 是一种具有口服活性的、选择性的和中枢神经系统 (CNS) 渗透性的 Rho激酶 (ROCK) 抑制剂 (ROCK2 IC50=3 nM)。Rho-Kinase-IN-2 可用于亨廷顿病的研究。 | |||||
| GC33310 | Rho-Kinase-IN-1 | 1035094-83-7 | ROCK | ||
Rho-Kinase-IN-1是一个rho激酶抑制剂，来自专利US20090325960A1，化合物1.008。 | |||||
| GC74316 | ATR kinase substrate peptide | - | ATM/ATR | ||
ATR kinase substrate peptide（化合物45）是ATR（共济失调毛细血管扩张和Rad3相关）蛋白激酶（Ki=6 nM）的有效和选择性抑制剂。 | |||||
| GC70451 | Rho-Kinase-IN-3 | 864082-23-5 | ROCK | ||
Rho-Kinase-IN-3（化合物12）是一种强效且选择性的Rho激酶（ROCK1）抑制剂，IC50值为8nM。 | |||||
| GC11292 | Mps1-IN-1 | 1125593-20-5 | Mps1 | ||
A selective Mps1 kinase inhibitor | |||||