关于 "Nucleoside Antimetabolite/Analogue" 的结果10+ 个结果

筛选:Autophagy×
  • GC16805 structure
    Gemcitabine
    CAS: 95058-81-4

    An anticancer nucleoside analog

    Autophagy
  • GC14961 structure
    Cytarabine hydrochloride
    CAS: 69-74-9

    A nucleoside analog and prodrug form of ara-CTP

    Autophagy
  • GC14366 structure
    Thioguanine
    CAS: 154-42-7

    Thioguanine是一种抗白血病和免疫抑制剂,对重组USP2和冠状病毒PLpro的IC 50 值分别为40μM和25μM。

  • GC10518 structure
    AICAR
    CAS: 2627-69-2

    AICAR(也称为 acadesine)是一种嘌呤核苷。

  • GC17694 structure
    Pemetrexed disodium hemipenta hydrate
    CAS: 357166-30-4

    Pemetrexed disodium hemipenta hydrate 是一种新型抗叶酸剂,LY231514 的五谷氨酸的 Ki 值分别为 1.3、7.2 和 65 nM,用于抑制胸苷酸合酶 (TS)、二氢叶酸还原酶 (DHFR) 和甘氨酰胺核糖核苷酸甲酰转移酶 (GARFT)。

    Autophagy
  • GC15219 structure
    Clofarabine
    CAS: 123318-82-1

    A ribonucleotide reductase and DNA polymerase-α inhibitor

  • GC35112 structure
    3'-Hydroxypterostilbene
    CAS: 475231-21-1

    3'-Hydroxypterostilbene (3'-HPT) is one of the active constituents of Sphaerophysa salsula and Pterocarpus marsupium which may be useful in treating different types of haematological malignancies. 3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 ?M for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways.

    Autophagy
  • GC14106 structure
    Adenosine
    CAS: 58-61-7

    Adenosine是一种内源性神经调节物质,包含腺嘌呤,通过β-N9-糖苷键与核糖分子(呋喃核糖)部分连接。

  • GC16267 structure
    6-Hydroxydopamine hydrobromide
    CAS: 636-00-0

    6-Hydroxydopamine hydrobromide (6-OHDA) 是儿茶酚胺、多巴胺和去甲肾上腺素的结构类似物,对儿茶酚胺能神经元发挥毒性作用。

  • GN10503 structure
    Piceatannol
    CAS: 10083-24-6

    Piceatannol(3,3 ',4,5 ' -反式三羟基二苯乙烯)是天然存在的白藜芦醇羟基化类似物。

    Autophagy