关于 "Nuclear Receptors" 的结果1+ 个结果

筛选:Aryl Hydrocarbon Receptor×
  • GC31732 structure
    Tapinarof (WBI 1001)
    CAS: 79338-84-4

    Tapinarof (GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505) is a natural agonist of aryl hydrocarbon receptor (AhR) and induces nuclear translocation of AhR in immortalized keratinocytes (HaCaT) with EC50 of 0.16 nM. Tapinarof induces cellular apoptosis in CD4+ T cells in a dosedependent manner with IC50 of 5.2 μM.

    Aryl Hydrocarbon Receptor