关于 "FAS" 的结果13 个结果
- Euphorbia Factor L1CAS: 76376-43-7
Euphorbia factor L1, a diterpenoid isolated from Euphorbia lathyris, inhibits osteoclastogenesis and induces osteoclast apoptosis.
- Euphorbia Factor L2CAS: 218916-51-9
Euphorbia factor L2 是从大戟种子中分离得到的一种赤藓烷二萜 (Euphorbia lathyris L.)，传统上用于治疗癌症。Euphorbia factor L2 显示强烈的细胞毒性并通过线粒体途径诱导细胞凋亡。
Apoptosis - Psoromic AcidCAS: 7299-11-8
An inhibitor of Rab geranylgeranyl transferase and P. falciparum FAS II enzymes
Apoptosis - trans-ChalconeCAS: 614-47-1
Trans-Chalcone, the backbone of flavonoids, also is a potent fatty acid synthase (FAS) with IC50 of 17.1 μg/mL, and α-amylase inhibitor, causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7, exerting antifungal and anticancer activities.
- Boc-Asp(OMe)-fluoromethyl ketoneCAS: 187389-53-3
Boc-Asp(OME)-Fluoromethyl Keton 是一种广泛的 caspase 抑制剂，可抑制 Fas 介导的吞噬作用和氧化破裂抑制，但不影响 IL-8 的趋化活性。
- (Rac)-IndoximodCAS: 26988-72-7
(Rac)-Indoximod(1-Methyl-DL-tryptophan)是吲哚胺-2,3-双加氧酶(IDO)抑制剂。(Rac)-Indoximod和IFN-γ联用显著降低了表达α-SMA的人心肌成纤维细胞活性，并通过上调IRF-1，Fas和FasL基因诱导凋亡(apoptosis)。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC15066 | Z-FA-FMK | 197855-65-5 | Calpains | ||
An inhibitor of cysteine proteases, including cathepsin B | |||||
| GC10528 | Salirasib | 162520-00-5 | Autophagy | ||
A Ras inhibitor with anti-cancer and anti-atherogenic activity | |||||
| GC38165 | Euphorbia Factor L1 | 76376-43-7 | Other Apoptosis | ||
Euphorbia factor L1, a diterpenoid isolated from Euphorbia lathyris, inhibits osteoclastogenesis and induces osteoclast apoptosis. | |||||
| GC60157 | Euphorbia Factor L2 | 218916-51-9 | Apoptosis | ||
Euphorbia factor L2 是从大戟种子中分离得到的一种赤藓烷二萜 (Euphorbia lathyris L.)，传统上用于治疗癌症。Euphorbia factor L2 显示强烈的细胞毒性并通过线粒体途径诱导细胞凋亡。 | |||||
| GN10142 | Lupeol | 545-47-1 | Other Apoptosis | ||
A dietary triterpene with anti-inflammatory and anticancer activity | |||||
| GC45758 | Paclitaxel octadecanedioate | 2089211-45-8 | G1 | ||
A prodrug form of paclitaxel | |||||
| GC18652 | FQI 1 | 599151-35-6 | Transcription Factors | ||
An inhibitor of Late SV40 Factor | |||||
| GC72103 | Kp7-6 | 629628-53-1 | Apoptosis | ||
Kp7-6是一种Fas模拟肽，是一种Fas/FasL拮抗剂。 | |||||
| GC18547 | Psoromic Acid | 7299-11-8 | Apoptosis | ||
An inhibitor of Rab geranylgeranyl transferase and P. falciparum FAS II enzymes | |||||
| GC15586 | AP1903 | 195514-63-7 | Other Apoptosis | ||
AP1903是一种二价"二聚化"化合物，可与FKBP结合并诱导Fas交联。 | |||||
| GC61896 | trans-Chalcone | 614-47-1 | Fatty Acid Synthase (FASN) | ||
Trans-Chalcone, the backbone of flavonoids, also is a potent fatty acid synthase (FAS) with IC50 of 17.1 μg/mL, and α-amylase inhibitor, causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7, exerting antifungal and anticancer activities. | |||||
| GC68787 | Boc-Asp(OMe)-fluoromethyl ketone | 187389-53-3 | Caspase | ||
Boc-Asp(OME)-Fluoromethyl Keton 是一种广泛的 caspase 抑制剂，可抑制 Fas 介导的吞噬作用和氧化破裂抑制，但不影响 IL-8 的趋化活性。 | |||||
| GC61750 | (Rac)-Indoximod | 26988-72-7 | IDO | ||
(Rac)-Indoximod(1-Methyl-DL-tryptophan)是吲哚胺-2,3-双加氧酶(IDO)抑制剂。(Rac)-Indoximod和IFN-γ联用显著降低了表达α-SMA的人心肌成纤维细胞活性，并通过上调IRF-1，Fas和FasL基因诱导凋亡(apoptosis)。 | |||||