关于 "Cancer stem cell" 的结果42+ 个结果

Chonglou Saponin VII (Dioscinin, Polyphyllin-VII, Paris saponin-VII), a kind of steroidal saponins from Chonglou (Rhizoma Paridis Chonglou), inhibits EMT and reduces the invasion of ovarian cancer cells via the GSK-3β/β-catenin signaling pathway.

Natural curcuminoid with roles in cancer and inflammation

Bruceine D, isolated from Brucea javanica (L.) Merr. (Simaroubaceae), shows antineoplastic properties in various human cancers including pancreas, breast, lung, blood, bone, and liver. Bruceine D induces apoptosis in human chronic myeloid leukemia K562 cells via mitochondrial pathway.

Y-27632 dihydrochloride 作为一种选择性 Rho 激酶抑制剂，是一种新型支气管扩张剂。

Triglycidyl Isocyanurate (Teroxirone, Tris(2,3-epoxypropyl) Isocyanurate, TGI, TGIC) is a triazene triepoxide with antineoplastic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl Isocyanurate alkylates and cross-links DNA, thereby inhibiting DNA replication. Triglycidyl Isocyanurate is also used in various polyester powder coatings in the metal finishing industry.

Natural curcuminoid with roles in Alzheimer’s, cancer, and inflammation

A Ras inhibitor with anti-cancer and anti-atherogenic activity

Docetaxel是紫杉烷类抗有丝分裂化疗药物,IC50为0.2 µM。

SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13 with IC50 of 99 nM and Kd of 98 nM for CDK12 and IC50 of 4.9 nM for CDK13. SR-4835 disables triple-negative breast cancer (TNBC) cells. SR-4835 promotes synergy with DNA-damaging chemotherapy and PARP inhibitors.

ICG001 是一种靶向 Wnt/β-catenin 通路的小分子抑制剂。

An inhibitor of cell proliferation

A cell-permeable PKC inhibitor

A cell-permeable Smac mimetic

Regulates cell cycle

Caspase-3 inhibitor,cell-permeable

A cell-permeable Smac mimetic

An inhibitor of cell proliferation

A cell-permeable inactivator of p53