GlpBio

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate

目录号: GC61257纯度: >95.00%
S-(1-Hydroxy-2-methylpropan-2-yl)methanesulfonothioate是一种谷胱甘肽可降解(cleavable)的ADClinker，用于抗体偶联药物(ADCs)，属于Alkyl-Chain类，是ADCs用于mAb附着的连接体部分。
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate
Cas No.: 2127875-65-2
规格价格库存数量操作
50mg¥4,320.00现货
1
100mg¥6,120.00现货
1
250mg¥8,820.00现货
1
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文献被引

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    187(9):2288-2304 (2024)
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产品描述 Description

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes[1].

[1]. Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
2127875-65-2
SMILES
CC(SS(C)(=O)=O)(C)CO
分子式
C5H12O3S2
分子量
184.28 g/mol
保存条件
4°C, protect from light, stored under nitrogen
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol