Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs)[1][2][3].
Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used as a label to measure the hydrodynamic radii of intravitreal anti-VEGF drugs[2].
[1]. Chen L, et al. Dual-color fluorescence and homogeneous immunoassay for the determination of human enterovirus 71. Anal Chem. 2011 Oct 1;83(19):7316-22.
[2]. Hirvonen LM, et al. Hydrodynamic Radii of Ranibizumab, Aflibercept and Bevacizumab Measured by Time-Resolved Phosphorescence Anisotropy. Pharm Res. 2016 Aug;33(8):2025-32.
[3]. HongfangGao, et al. Highly selective electrogenerated chemiluminescence biosensor for simultaneous detection of matrix metalloproteinase-2 and matrix metalloproteinase-7 in cell secretions. Sensors and Actuators B: Chemical, December 2017, 69-76.