GlpBio

Hexokinase

Hexokinase(己糖激酶)

Hexokinases phosphorylates glucose to generate glucose-6-phosphate, the initial step in glucose metabolism. HK1 and HK2 are two subtypes of mitochondrial hexokinases whichs are also involved in antiapopotic and cell survival.

Hexokinase 相关产品(4)

  • GC17430 structure
    GC174302-Deoxy-D-glucose
    CAS: 154-17-6
    纯度: >98.00%

    2-Deoxy-D-glucose (2DG)，是一种葡萄糖类似物，作为竞争性糖酵解抑制剂。

  • GC11532 structure
    GC11532Lonidamine
    CAS: 50264-69-2
    纯度: >99.00%

    Lonidamine是一种己糖激酶、线粒体丙酮酸载体（在分离的大鼠肝脏线粒体中Ki为2.5μM）和质膜单羧酸转运蛋白抑制剂，同时还抑制线粒体复合物 II。

  • GC15523 structure
    GC155233-Bromopyruvic acid
    CAS: 1113-59-3
    纯度: >97.00%

    3-Bromopyruvic acid是一种抗肿瘤剂，能够抑制有氧糖酵解和氧化磷酸化过程，对丙酮酸脱氢酶（PDH）和异柠檬酸脱氢酶（IDH）的IC 50 值分别为15μM和35μM。

  • GC70717 structure
    GC70717Benitrobenrazide (Hexokinase 2 inhibitor 1)
    CAS: 2454676-05-0
    纯度: >98.00%

    Benitrobenrazide (Hexokinase 2 inhibitor 1)通过直接靶向HK2来抑制糖酵解。