GlpBio

5-Lipoxygenase

5-Lipoxygenase(5-脂氧合酶)

5-lipoxygenase catalyzes oxidation of AA at the 5-position to yield 5-HpETE and is a current target for pharmaceutical intervention in a number of diseases such as asthma, atherosclerosis and several cancers.

5-Lipoxygenase 相关产品(10)

  • GC10451 structure
    GC10451U-73122
    CAS: 112648-68-7
    纯度: >98.00%

    U-73122是有效的、选择性的磷脂酶C（PLC）抑制剂，IC 50 值约为1-2.1μM，也可抑制5-脂氧合酶（5-LO）。

  • GC14435 structure
    GC14435Zileuton sodium
    CAS: 118569-21-4

    A reversible inhibitor of 5-lipoxygenase

  • GC14751 structure
    GC14751Malotilate
    CAS: 59937-28-9
    纯度: >99.50%

    A hepatoprotective agent

  • GC16014 structure
    GC16014Zileuton
    CAS: 111406-87-2
    纯度: >99.00%

    Zileuton是一种苯并噻吩N-羟基脲类化合物，作为口服5-脂氧合酶抑制剂。

  • GC10709 structure
    GC10709BW-B 70C
    CAS: 134470-38-5

    BW-B 70C 是一种有效的、选择性的和具有口服活性的花生四烯酸 5-脂氧合酶抑制剂。

  • GC12205 structure
    GC12205PD 146176
    CAS: 4079-26-9
    纯度: >98.00%

    PD 146176 是一种有效的选择性网织红细胞 15-LOX-1 抑制剂。

  • GC12232 structure
    GC12232BAY-X 1005
    CAS: 128253-31-6
    纯度: >98.50%

    BAY-X 1005 (BAY X 1005; DG-031) 是一种具有口服活性的选择性 5-脂氧合酶活化蛋白 (FLAP) 抑制剂。

  • GC12277 structure
    GC12277MK 886
    CAS: 118414-82-7
    纯度: >99.50%

    A potent, selective inhibitor of FLAP

  • GC15961 structure
    GC15961β-acetyl-Boswellic Acid
    CAS: 5968-70-7

    An anti-inflammatory pentacyclic triterpene

  • GC17951 structure
    GC179512-TEDC
    CAS: 132465-10-2

    5-, 12-, and 15-lipoxygenase inhibitor