GlpBio

(R)-ML375

目录号: GC70581纯度: >98.00%
(R)-ML375R-VU0483253是ML375的对映异构体。
(R)-ML375
Cas No.: 1488362-56-6
规格价格库存数量操作
5 mg¥891.00现货
1
10 mg¥1,498.00现货
1
25 mg¥3,159.00现货
1
50 mg¥5,386.00现货
1
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文献被引

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产品描述 Description

(R)-ML375 ((R)-VU0483253) is an enantiomer of ML375 . (R)-ML375 is devoid of M5 mAChR activity (hM5, IC50>30 μM).

References:
[1]. Patrick R Gentry, et al. Discovery of the first M5-selective and CNS penetrant negative allosteric modulator (NAM) of a muscarinic acetylcholine receptor: (S)-9b-(4-chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydro-1H-imidazo[2,1-a]isoindol-5(9bH)-one (ML375). J Med Chem. 2013 Nov 27;56(22):9351-5.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
1488362-56-6
分子式
C23H15ClF2N2O2
分子量
424.83 g/mol
溶解性
DMSO : 100 mg/mL (235.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol