GlpBio

Q1-SM-102 (iodide)

目录号: GC92068纯度: >98.00%同义词: Q<sub>1</sub>-CAY10779; Q<sub>1</sub>-Lipid H; Q<sub>1</sub>-LNP-102
Q1-SM-102 (iodide)是可电离阳离子脂质SM-102的阳离子季铵脂质衍生物，其已用于产生体内使用的脂质纳米颗粒LNPs。
Q1-SM-102 (iodide)
规格价格库存数量操作
1 mg¥420.00现货
1
5 mg¥1,372.00现货
1
10 mg¥2,520.00现货
1
电话: 400-920-5774Email: sales@glpbio.cn

文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

Q1-SM-102 is a cationic quaternary ammonium lipid derivative of the ionizable cationic lipid SM-102 that has been used in the generation of lipid nanoparticles (LNPs) for use in vivo.1 LNPs containing Q1-SM-102 and SM-102 as a cationic lipid pair (CLP) and encapsulating mRNA encoding a luciferase reporter induce luciferase expression in the lungs and spleen in mice.

References:
[1]. Zeng, G., He, Z., Yang, H., et al.Cationic lipid pairs enhance liver-to-lung tropism of lipid nanoparticles for in vivo mRNA deliveryACS Appl. Mater. Interfaces16(20)25698-25709(2024).

产品文档 Product Documents

Purity:>98.00%Appearance:A solution in ethanol

化学性质Chemical Properties

同义词
Q<sub>1</sub>-CAY10779; Q<sub>1</sub>-Lipid H; Q<sub>1</sub>-LNP-102
化学名
8-(heptadecan-9-yloxy)-N-(2-hydroxyethyl)-N-methyl-8-oxo-N-(6-oxo-6-(undecyloxy)hexyl)octan-1-aminium, monoiodide
SMILES
OCC[N+](CCCCCCCC(OC(CCCCCCCC)CCCCCCCC)=O)(C)CCCCCC(OCCCCCCCCCCC)=O.[I-]
分子式
C45H90NO5 ? I
分子量
852.1 g/mol
溶解性
Chloroform: Sparingly Soluble: 1-10 mg/ml
保存条件
-20&#176;C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol