Prexigebersen sodium

目录号: GC73450纯度: >95.00%同义词: BP1001 sodium
Prexigebersen sodium是一种反义寡核苷酸,旨在抑制Grb2(生长因子受体结合蛋白2)的蛋白质合成。

Prexigebersen sodium
规格价格库存数量操作
1 mg¥432.00现货
1
5 mg¥1,260.00现货
1
10 mg¥2,016.00现货
1

文献被引

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    610, 366–372 (2022)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    31, 1291–1307 (2021)

产品描述 Description

Prexigebersen sodium is an antisense oligonucleotide designed to inhibit protein synthesis of Grb2 (growth factor receptor bound protein 2).

References:
[1]. Maro Ohanian, Tara L. Lin, Ellen Ritchie, et al. Pierce, Ana Tari Ashizawa, Hagop Kantarjian, Jorge E. Cortes, Gail J. Roboz; Safety and Efficacy of Lower Intensity Induction Therapy with Intravenous Prexigebersen (BP1001) in Patients with High-Risk and Relapsed/Refractory Acute Myeloid Leukemia (AML).Blood2021; 138 (Supplement 1): 1281. [2]. Tremblay G, Khalafaghian G, Legault J, Nielsen P, Bartlett A. Dual ligation bridization assay for the specific determination of oligonucleotide therapeutics. Bioanalysis. 2011;3(5):499-508.

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

同义词
BP1001 sodium
分子式
C177H206N63Na18O110P17
分子量
5916.25 g/mol
溶解性
H<sub>2</sub>O : ≥ 100 mg/mL (16.90 mM)
保存条件
-20&#176;C, sealed storage, away from moisture
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol