GLPBio

PQQ-trimethylester

目录号: GC73905纯度: >95.00%同义词: PQQ-TME
PQQ-trimethylester (pq - tme)是一种合成化合物，是吡咯喹啉醌（PQQ）的三甲醚衍生物。
PQQ-trimethylester
Cas No.: 74447-88-4
规格价格库存数量操作
5 mg¥450.00现货
1
10 mg¥630.00现货
1
25 mg¥1,242.00现货
1
50 mg¥1,980.00现货
1
100 mg¥3,150.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

PQQ-trimetlester (PQQ-TME) is a synthetic compound that is a trimetlester derivative of pyrroloquinoline quinone (PQQ). PQQ-trimetlester has twice the blood-brain barrier permeability of PQQ in vitro. In addition, PQQ-trimetlester shows strong inhibitory activity against α-synuclein, amyloid β1-42 (Aβ1-42) and prion protein fibrillation. PQQ-trimetlester can be used in the study of neurodegenerative diseases.

References:
[1]. Tsukakoshi K, et al. Esterification of PQQ enhances blood-brain barrier permeability and inhibitory activity against amyloidogenic protein fibril formation[J]. ACS Chemical Neuroscience, 2018, 9(12): 2898-2903.

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
74447-88-4
同义词
PQQ-TME
分子式
C17H12N2O8
分子量
372.29 g/mol
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol