pJAK2(1001-1013) is a SOCS1/3 antagonist. pJAK2(1001–1013) plays a positive role in antiviral immune response by inhibiting the negative regulatory effect of SOCS proteins and enhancing the JAK/STAT signaling pathway[1]
References:
[1]. Ahmed C M, et al. A SOCS1/3 antagonist peptide protects mice against lethal infection with influenza A virus[J]. Frontiers in immunology, 2015, 6: 574.