Photoclick Myristic Acid is a cell-permeable photoreactive probe for protein myristoylation.1,2 It contains a terminal clickable alkyne moiety and a photoactivatable diazirine group at carbon 10 that allow its incorporation into myristylated proteins and photo-activated cross-linking of their interacting partners, respectively.
1.Peng, T., and Hang, H.C.Bifunctional fatty acid chemical reporter for analyzing S-palmitoylated membrane protein-protein interactions in mammalian cellsJ. Am. Chem. Soc.137(2)556-559(2015) 2.Chuh, K.N., Batt, A.R., and Pratt, M.R.Chemical methods for encoding and decoding of posttranslational modificationsCell. Chem. Bio.23(1)86-107(2016)