GlpBio

PG-11047 tetrahydrochloride

目录号: GC74053纯度: >98.00%同义词: CGC-11047 tetrahydrochloride
PG-11047 tetrahydrochloride（CGC-11047）是一种多胺类似物，是天然多胺精胺的无功能竞争对手。
PG-11047 tetrahydrochloride
Cas No.: 206991-64-2
规格价格库存数量操作
1 mg¥1,188.00现货
1
5 mg¥3,573.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    610, 366–372 (2022)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities.

References:
[1]. Wen-Lin Kuo, et al. A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047. BMC Med. 2009 Dec 14;7:77.
[2]. Murray Stewart T, et al. A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma. Cancer Chemother Pharmacol. 2021 Jan;87(1):135-144.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
206991-64-2
同义词
CGC-11047 tetrahydrochloride
分子式
C14H36Cl4N4
分子量
402.27 g/mol
溶解性
H<sub>2</sub>O : ≥ 30 mg/mL (74.58 mM)
保存条件
-20&#176;C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol