GlpBio

Pantothenate-AMC

目录号: GC91982纯度: >95.00%同义词: Pantothenate-7-amino-4-methylcoumarin
Pantothenate-AMC是缬氨酸-1的荧光底物，缬氨酸-1是一种参与l -泛酸循环的酶。
Pantothenate-AMC
Cas No.: 1224691-12-6
规格价格库存数量操作
1 mg¥910.00现货
1
5 mg¥4,102.00现货
1
10 mg¥7,280.00现货
1
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文献被引

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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

Pantothenate-AMC is a fluorogenic substrate for vanin-1, an enzyme involved in the recycling of L-pantothenic acid.1 Upon enzymatic cleavage by vanin-1, 7-amino-7-methylcoumarin (AMC) is released and its fluorescence can be used to quantify vanin-1 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

References:
[1]. Ruan, B.H., Cole, D.C., Wu, P., et al.A fluorescent assay suitable for inhibitor screening and vanin tissue quantificationAnal. Biochem.399(2)284-292(2010).

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
1224691-12-6
同义词
Pantothenate-7-amino-4-methylcoumarin
化学名
(2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino]-3-oxopropyl]-butanamide
SMILES
CC(C1=CC=C(NC(CCNC([C@H](O)C(C)(C)CO)=O)=O)C=C1O2)=CC2=O
分子式
C19H24N2O6
分子量
376.4 g/mol
溶解性
Acetonitrile: Slightly soluble: 0.1-1 mg/ml,DMSO: Sparingly soluble: 1-10 mg/ml,Water: Slightly soluble: 0.1-1 mg/ml
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol