GlpBio

P9R (trifluoroacetate salt)

目录号: GC92121纯度: >95.00%
P9R (trifluoroacetate salt)是一种具有抗病毒活性的肽。
P9R (trifluoroacetate salt)
规格价格库存数量操作
1 mg¥910.00现货
1
5 mg¥4,102.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

P9R is a peptide with antiviral activity.1 It inhibits viral replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Middle East respiratory syndrome coronavirus (MERS-CoV), SARS-CoV, influenza A subtypes H1N1 and H7N9, and rhinovirus in plaque reduction assays (IC50s = 0.9, 2.2, 4.2, 0.6, 0.9, and 5.7 ?g/ml, respectively). In vivo, P9R (50 ?g/animal three times over two days) increases survival and reduces H1N1 particle-forming units (PFUs) in the lungs to a similar extent as the influenza neuraminidase inhibitor zanamivir in H1N1-infected mice.

References:
[1]. Zhao, H., To, K.K.W., Sze, K.-H., et al.A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2Nat. Commun.11(1)4252(2020).

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

化学名
L-asparaginylglycyl-L-alanyl-L-isoleucyl-L-cysteinyl-L-tryptophylglycyl-L-prolyl-L-cysteinyl-L-prolyl-L-threonyl-L-alanyl-L-phenylalanyl-L-arginyl-L-glutaminyl-L-isoleucylglycyl-L-asparaginyl-L-cysteinylglycyl-L-arginyl-L-phenylalanyl-L-arginyl-L-valyl-L-arginyl-L-cysteinyl-L-cysteinyl-L-arginyl-L-isoleucyl-L-arginine, trifluoroacetate
SMILES
OC(C(F)(F)F)=O.O=C(NCC(N[C@H](C(N[C@@](C(N[C@@H](CS[H])C(N[C@@H](CC1=CNC2=C1C=CC=C2)C(NCC(N3CCC[C@H]3C(N[C@@H](CS[H])C(N4CCC[C@H]4C(N[C@]([C@H](O)C)([H])C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@](C(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CS[H])C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CS[H])C(N[C@@H](CS[H])C(N[C@@H](CCCNC(N)=N)C(N[C@@](C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)([H])[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)([H])[C@@H](C)CC)=O)=O)=O)CC6=CC=CC=C6)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)([H])[C@@H](C)CC)=O)C)=O)[C@H](CC(N)=O)N[H]
分子式
C144H232N52O35S5 ? XCF3COOH
分子量
3412.1 g/mol
溶解性
Water: Soluble
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol