(+)-Oxanthromicin is an enantiomer of the rare Streptomyces metabolite (-)-oxanthromicin. [1] It inhibits K-Ras plasma membrane localization in MDCK cells with an IC50 value of 62.5 μM.
Referene:
[1]. Salim, A.A., Xiao, X., Cho, K.-J., et al. Rare Streptomyces sp. polyketides as modulators of K-Ras localisation. Org. Biomol. Chem. 12(27), 4872-4878 (2014).
















