OVA Peptide 323-339 is an important immunogenic epitope peptide of ovalbumin (OVA). It serves as both a T-cell epitope and a B-cell epitope. As a T-cell epitope, OVA Peptide 323-339 can be presented by MHC class II molecules to activate CD4⁺ T cells. As a B-cell epitope, OVA Peptide 323-339 can be recognized by IgE antibodies. OVA Peptide 323-339 can be used to establish mouse models of allergy[1].
References:
[1] Sun LZ, Elsayed S, Aasen TB, et al. Comparison between ovalbumin and ovalbumin peptide 323-339 responses in allergic mice: humoral and cellular aspects. Scand J Immunol. 2010 May;71(5):329-35.
OVA Peptide 323-339是卵清蛋白（OVA）的一个重要免疫表位肽段，OVA Peptide 323-339既是T细胞表位，也是B细胞表位。作为T细胞表位，OVA Peptide 323-339可被MHC II类分子呈递，激活 CD4⁺ T 细胞；作为B细胞表位，OVA Peptide 323-339能被IgE抗体识别。可用于建立小鼠过敏模型[1]。