Ovalbumin (257-264) is a synthetic peptide fragment corresponding to the mouse MHC class I (H-2Kb) CD8+ T cell-restricted epitope of chicken ovalbumin.1,2 It is presented by H-2Kb dominant T cells and has been used to induce CD8+ T cell responses in vitro and in vivo.1,2,3
1.Wick, M.J., and Pfeifer, J.D.Major histocompatibility complex class I presentation of ovalbumin peptide 257-264 from exogenous sources: Protein context influences the degree of TAP-independent presentationEur. J. Immunol.26(11)2790-2799(1996) 2.Chaoul, N., and Dadglio, G.Antigen-specific in vivo killing assayMethods Mol. Biol.232555-64(2021) 3.Berguer, P.M., Alzogaray, V.A., Rossi, A.H., et al.A polymeric protein induces specific cytotoxicity in a TLR4 dependent manner in the absence of adjuvantsPLoS One7(9)e45705(2012)