GlpBio

Ophiobolin A

目录号: GC11782纯度: >95.00%同义词: 蛇孢菌素A,Cochliobolin,NSC 114340
A calmodulin antagonist
Ophiobolin A
Cas No.: 4611-05-6
规格价格库存数量操作
1mg¥4,235.00现货
1
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文献被引

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产品描述 Description

Ophiobolin A, a fungal metabolite and a phytotoxin, is a potent and irreversibly inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase, with an IC50 value of 9 μM. Ophiobolin A antimicrobial and anticancer activity[1].

References:
[1]. Leung PC, et al. Ophiobolin A. A natural product inhibitor of calmodulin. J Biol Chem. 1984 Mar 10;259(5):2742-7

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
4611-05-6
同义词
蛇孢菌素A,Cochliobolin,NSC 114340
化学名
(2'S,3'S,3aR,5'R,6aS,9R,9aS,10aR)-1,3a,4,4',5',6a,7,8,9,9a,10,10a-dodecahydro-9-hydroxy-3',9,10a-trimethyl-5'-spiro[dicyclopenta[a,d]cyclooctene-3(2H),2'(3'H)-furan]-6-carboxaldehyde
SMILES
C[C@H]1C[C@@H](O[C@]12[C@]3([H])C/C=C([C@]([H])([C@]([H])(C[C@]3(CC2)C)[C@](C4)(C)O)C4=O)/C([H])=O)/C=C(C)\C
分子式
C25H36O4
分子量
400.6 g/mol
溶解性
Soluble in ethanol;Soluble in methanol;Soluble in DMSO;Soluble in dimethyl formamide
保存条件
Store at -20°C,protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol