ODN 2007, a class B CpG ODN (oligodeoxynucleotide), is a Showed a cumulative mortality rate of 15.0% in treated group while the control group reached 42.1%.
Showed a significant decrease in the expression levels of all intestinal immune-related genes such as TNF、IFNg1-2、IL-1β、IL-10, especially IL-1β decreased by 99.88%.
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