GlpBio

NVOC cage-TMP-Halo

目录号: GC71274纯度: >96.00%
NVOC cage-TMP-Halo是一种细胞渗透性和光激活性的蛋白质二聚化诱导剂。
NVOC cage-TMP-Halo
Cas No.: 2137894-98-3
规格价格库存数量操作
1 mg¥540.00现货
1
5 mg¥1,530.00现货
1
10 mg¥2,430.00现货
1
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文献被引

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    641, 529–536 (2025)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

NVOC cage-TMP-Halo is a cell-permeable and photoactivatable protein dimerization inducer. NVOC cage-TMP-Halo can rapidly and reversibly control protein localization in living cells. NVOC cage-TMP-Halo can be used for dynamic cellular processes research.

NVOC cage-TMP-Halo (20μM, 60 min) exhibited dramatic recruitment of mCherry-eDHFR to centromeres with a t1/2 of ~ 15 s of expressing CENPB-GFP-Haloenzyme and mCherry-eDHFR HeLa cell line[1].
NVOC cage-TMP-Halo (20μM, 15, 30, and 60 min) has the power for spatially precise manipulation of protein localization in HeLa cell line[1].

References:
[1]. Ballister ER, et al. Localized light-induced protein dimerization in living cells using a photocaged dimerizer. Nat Commun. 2014 Nov 17;5:5475.

产品文档 Product Documents

Purity:>96.00%

化学性质Chemical Properties

CAS 号
2137894-98-3
分子式
C40H56ClN7O13
分子量
878.36 g/mol
溶解性
DMSO : 150 mg/mL (170.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol