GLPBio

NaV1.2/1.6 channel blocker-1

目录号: GC75469纯度: >98.00%
NaV1.2/1.6 channel blocker-1 是一种有效的 NaV1.2/1.6 channel 阻滞剂，抑制 rNaV1.6 和 hNaV1.2 的 IC50 值分别为 9.8 和 24.4 μM。NaV1.2/1.6 channel blocker-1 可用于全身性癫痫的研究。
NaV1.2/1.6 channel blocker-1
Cas No.: 1199944-04-1
规格价格库存数量操作
5 mg¥670.00现货
1
10 mg¥1,015.00现货
1
25 mg¥2,030.00现货
1
50 mg¥3,010.00现货
1
100 mg¥4,500.00现货
1
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文献被引

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产品描述 Description

NaV1.2/1.6 channel blocker-1 is a potent NaV1.2/1.6 channel blocker, with IC50s of 9.8 and 24.4 μM for rNaV1.6 and hNaV1.2, respectively. NaV1.2/1.6 channel blocker-1 can be used for the research of generalized epilepsy[1].

References:
[1]. Rivara M, et, al. Biological Evaluation of Imidazobenzoxazines, Imidazobenzoxazin-5-ones and Imidazobenzoxazin-5-thiones as Sodium Channel Blockers. Letters in Drug Design Discovery, 2014, 11, 90-97.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
1199944-04-1
分子式
C14H14N2OS
分子量
258.34 g/mol
溶解性
DMSO: 12.5 mg/mL (48.39 mM; ultrasonic and warming and heat to 60°C)
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol