GlpBio

NAG-thiazoline

目录号: GC49144纯度: >98.00%同义词: N-乙酰-葡糖胺基噻唑啉
An OGA inhibitor
NAG-thiazoline
Cas No.: 179030-22-9
规格价格库存数量操作
1mg¥288.00现货
1
5mg¥924.00现货
1
10mg¥1,632.00现货
1
25mg¥3,542.00现货
1
50mg¥5,298.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

NAG-thiazoline is an inhibitor of O-GlcNAcase (OGA; Ki = 180 nM).1 It is active against V. campbellii (MIC = 0.5 µM).2

1.Macauley, M.S., and Vocadlo, D.J.Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcaseBiochim. Biophys. Acta1800(2)107-121(2010) 2.Meekrathok, P., Stubbs, K.A., Aunkham, A., et al.NAG-thiazoline is a potent inhibitor of the Vibrio campbellii GH20 β-N-AcetylglucosaminidaseFEBS J.287(22)4982-4995(2020)

产品文档 Product Documents

Purity:>98.00%Appearance:A solution in ethanol

化学性质Chemical Properties

CAS 号
179030-22-9
同义词
N-乙酰-葡糖胺基噻唑啉
SMILES
O[C@@H]1[C@]2([H])[C@](SC(C)=N2)([H])O[C@@H]([C@H]1O)CO
分子式
C8H13NO4S
分子量
219.3 g/mol
溶解性
DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 5 mg/ml
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol