GlpBio

N-desethyl-N-methyl Vardenafil

目录号: GC49683纯度: >95.00%同义词: N-去乙基-N-甲基伐地那非
A potential impurity found in commercial preparations of vardenafil
N-desethyl-N-methyl Vardenafil
Cas No.: 224785-87-9
规格价格库存数量操作
1 mg¥2,538.00现货
1
5 mg¥10,596.00现货
1
500 µg¥1,412.00现货
1
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文献被引

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    183(7):1867-1883 (2020)
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产品描述 Description

N-desethyl-N-methyl Vardenafil is a potential impurity found in commercial preparations of the phosphodiesterase 5 (PDE5) inhibitor vardenafil .1 It is also a PDE5 inhibitor (IC50 = 2 nM).2

1.Subba Rao, D.V., Surendranath, K.V., Radhakrishnanand, P., et al.A stability indicating LC method for vardenafil HClChromatographia68(9)829-835(2008) 2.Haning, H., NiewÖhner, U., Schenke, T., et al.Comparison of different heterocyclic scaffolds as substrate analog PDE5 inhibitorsBioorg. Med. Chem. Lett.15(17)3900-3907(2005)

产品文档 Product Documents

Purity:>95.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
224785-87-9
同义词
N-去乙基-N-甲基伐地那非
SMILES
O=C1N=C(C2=C(OCC)C=CC(S(=O)(N3CCN(CC3)C)=O)=C2)NN4C(CCC)=NC(C)=C14
分子式
C22H30N6O4S
分子量
474.6 g/mol
溶解性
Acetonitrile: soluble,Methanol: soluble
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol