Myomodulin A is a gastropod neuropeptide.[1] It is found in gastropod ventral lobe neurons, neural elements of the accessory radula closer (ARC) muscle, and penis nerve.1,2,3 Myomodulin A is biosynthesized by ARC motor neurons in A. californica and potentiates motor neuron-elicited contractions of the A. californica buccal mass ARC.[2] Myomodulin A also increases the relaxation rate of electrically evoked muscle contractions in L. stagnalis penis retractor muscle.[3]
References:
[1].Miller, M.W., Beushausen, S., Vitek, A., et al.The myomodulin-related neuropeptides: Characterization of a gene encoding a family of peptide cotransmitters in AplysiaJ. Neurosci.13(8)3358-3367(1993).
[2].Cropper, E.C., Tenenbaum, R., Kolks, M.A., et al.Myomodulin: a bioactive neuropeptide present in an identified cholinergic buccal motor neuron of AplysiaProc. Natl. Acad. Sci. USA84(15)5483-5486(1987).
[3].Li, K.W., van Golen, F.A., van Minnen, J., et al.Structural identification, neuronal synthesis, and role in male copulation of myomodulin-A of Lymnaea: A study involving direct peptide profiling of nervous tissue by mass spectrometryBrain Res. Mol. Brain Res.25(3-4)355-358(1994).