Murrayone is a coumarin that has been found in L. japonicus and has fungicidal and antiplatelet activities.1,2 It is active against the plant pathogenic fungi T. cucumeris and C. capsici (EC50s = 46.9 and 24.9 ?g/ml, respectively) but not S. sclerotiorum, B. cinerea, or F. graminearum (EC50s = >50 ?g/ml for all).2 Murrayone also inhibits ADP-induced platelet aggregation in vitro.1
1.Yang, H., Zhou, Q.-m., Peng, C., et al.Coumarins from Leonurus japonicus and their anti-platelet aggregative activityZhongguo Zhong Yao Za Zhi39(22)4356-4359(2014) 2.Song, P.-P., Zhao, J., Liu, Z.-L., et al.Evaluation of antifungal activities and structure-activity relationships of coumarin derivativesPest Manag. Sci.73(1)94-101(2017)