GlpBio

Molsidomine (SIN-10)

目录号: GC32579纯度: >99.00%同义词: 吗多明; SIN-10; Morsydomine
An NO-releasing prodrug
Molsidomine (SIN-10)
Cas No.: 25717-80-0
规格价格库存数量操作
500mg¥536.00现货
1
10mM (in 1mL DMSO)¥589.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

Molsidomine is a NO-releasing prodrug. Liver esterases convert molsidomine to the active metabolite, SIN-1 (half-life in plasma is 1-2 hours), which then releases NO.1,2

1.Nitz, R.E., and Fiedler, V.Molsidomine: Alternative approaches to treat myocardial ischemiaPharmacotherapy728-37(1987) 2.Rosenkranz, B., Winkelmann, B.R., and Parnham, M.J.Clinical pharmacokinetics of molsidomineClin. Pharmacokinet.30(5)372-384(1996)

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

CAS 号
25717-80-0
同义词
吗多明; SIN-10; Morsydomine
SMILES
O=C([N-]C1=C[N+](N2CCOCC2)=NO1)OCC
分子式
C9H14N4O4
分子量
242.23 g/mol
溶解性
DMSO : ≥ 42 mg/mL (173.39 mM)
保存条件
Store at -20°C,protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol