Mechercharmycin A is a cyclic peptide originally isolated from Thermoactinomyces that has anticancer activity.[1] It induces cytotoxicity in A549 lung cancer and Jurkat leukemia cells (IC50s = 40 and 46 nM, respectively).
References:
[1].Kanoh, K., Matsuo, Y., Adachi, K., et al.Mechercharmycins A and B, cytotoxic substances from marine-derived Thermoactinomyces sp. YM3-251J. Antibiot. (Tokyo)58(4)289-292(2005).
















